In vitro pharmacodynamic characteristics of nystatin including time-kill and postantifungal effect

被引:34
作者
Gunderson, SM
Hoffman, H
Ernst, EJ
Pfaller, MA
Klepser, ME
机构
[1] Univ Iowa, Coll Pharm, Iowa City, IA 52242 USA
[2] Univ Iowa, Coll Med, Dept Pathol, Iowa City, IA 52242 USA
关键词
D O I
10.1128/AAC.44.10.2887-2890.2000
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Four Candida albicans isolates and six non-albicans Candida isolates were evaluated by time-kill methods to characterize the relationship between nystatin concentrations, the rate and extent of fungicidal activity, and the postantifungal effect (PAFE). Against Candida species, nystatin exhibits concentration-dependent fungicidal activity and a pronounced PAFE.
引用
收藏
页码:2887 / 2890
页数:4
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