Research and development of universal influenza vaccines

被引:100
作者
Du, Lanying [1 ]
Zhou, Yusen [2 ]
Jiang, Shibo [1 ]
机构
[1] New York Blood Ctr, Lindsley F Kimball Res Inst, New York, NY 10065 USA
[2] Beijing Inst Microbiol & Epidemiol, Beijing 100071, Peoples R China
关键词
Influenza; Vaccine; M2e; HA; A VIRUS; MONOCLONAL-ANTIBODIES; PROTECT MICE; M2; PROTEIN; LETHAL CHALLENGE; H5N1; HEMAGGLUTININ; IMMUNIZATION; PEPTIDE; NUCLEOPROTEIN;
D O I
10.1016/j.micinf.2010.01.001
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The continuous threat of influenza pandemics determines the urgency and necessity to develop safe and effective vaccines against divergent influenza viruses. This review describes the advancements in the research and development of universal influenza vaccines based on the relatively conserved sequences of M2e. HA, and other proteins of influenza viruses. (C) 2010 Elsevier Masson SAS All rights reserved
引用
收藏
页码:280 / 286
页数:7
相关论文
共 45 条
[1]   A universal epitope-based influenza vaccine and its efficacy against H5N1 [J].
Adar, Y. ;
Singer, Y. ;
Levi, R. ;
Tzehoval, E. ;
Perk, S. ;
Banet-Noach, C. ;
Nagar, S. ;
Amon, R. ;
Ben-Yedidia, T. .
VACCINE, 2009, 27 (15) :2099-2107
[2]   Immunization with influenza A NP-expressing vaccinia virus recombinant protects mice against experimental infection with human and avian influenza viruses [J].
Altstein, AD ;
Gitelman, AK ;
Smirnov, YA ;
Piskareva, LM ;
Zakharova, LG ;
Pashvykina, GV ;
Shmarov, MM ;
Zhirnov, OP ;
Varich, NP ;
Ilyinskii, PO ;
Shneider, AM .
ARCHIVES OF VIROLOGY, 2006, 151 (05) :921-931
[3]   Recombinant Vesicular Stomatitis Virus Expressing Influenza Nucleoprotein Induces CD8 T-Cell Responses That Enhance Antibody-Mediated Protection after Lethal Challenge with Influenza Virus [J].
Barefoot, Brice E. ;
Sample, Christopher J. ;
Ramsburg, Elizabeth A. .
CLINICAL AND VACCINE IMMUNOLOGY, 2009, 16 (04) :488-498
[4]   A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses [J].
Chen, Ming-Wei ;
Cheng, Ting-Jen Rachel ;
Huang, Yaoxing ;
Jan, Jia-Tsrong ;
Ma, Shiou-Hwa ;
Yu, Alice L. ;
Wong, Chi-Huey ;
Ho, David D. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (36) :13538-13543
[5]   Comparing the ability of a series of viral protein-expressing plasmid DNAs to protect against H5N1 influenza virus [J].
Chen, Quanjiao ;
Kuang, Haimen ;
Wang, Huadong ;
Fang, Fang ;
Yang, Zhongdong ;
Zhang, Zhiping ;
Zhang, Xianen ;
Chen, Ze .
VIRUS GENES, 2009, 38 (01) :30-38
[6]   Universal antibodies and their applications to the quantitative determination of virtually all subtypes of the influenza A viral hemagglutinins [J].
Chun, Stella ;
Li, Changgui ;
Van Domselaar, Gary ;
Wang, Junzhi ;
Farnsworth, Aaron ;
Cui, Xiaoyu ;
Rode, Harold ;
Cyr, Terry D. ;
He, Runtao ;
Li, Xuguang .
VACCINE, 2008, 26 (48) :6068-6076
[7]   An influenza A vaccine based on tetrameric ectodomain of matrix protein 2 [J].
De Filette, Marina ;
Martens, Wouter ;
Roose, Kenny ;
Deroo, Tom ;
Vervalle, Frederik ;
Bentahir, Mostafa ;
Vandekerckhove, Joel ;
Fiers, Walter ;
Saelens, Xavier .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (17) :11382-11387
[8]  
DE FM, 2008, VACCINE, V26, P6503
[9]   Development of a universal influenza A vaccine based on the M2e peptide fused to the papaya mosaic virus (PapMV) vaccine platform [J].
Denis, Jerome ;
Acosta-Ramirez, Elizabeth ;
Zhao, Yinghi ;
Hamelin, Marie-Eve ;
Koukavica, Irena ;
Baz, Mariana ;
Abed, Yacine ;
Savard, Christian ;
Pare, Christine ;
Macias, Constantino Lopez ;
Boivin, Guy ;
Leclerc, Denis .
VACCINE, 2008, 26 (27-28) :3395-3403
[10]   Detection of circulating Asian H5N1 viruses by a newly established monoclonal antibody [J].
Du, Anariwa ;
Daidoji, Tomo ;
Koma, Takaaki ;
Ibrahim, Madiha S. ;
Nakamura, Shota ;
de Silva, U. Chandimal ;
Ueda, Mayo ;
Yang, Cheng-Song ;
Yasunaga, Teruo ;
Ikuta, Kazuyoshi ;
Nakaya, Takaaki .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2009, 378 (02) :197-202