A general enzymatic method for the synthesis of natural and "unnatural" UDP- and TDP-nucleotide sugars

被引：83

作者：

Jiang, JQ

Biggins, JB

Thorson, JS

机构：

[1] Mem Sloan Kettering Canc Ctr, Lab Biosynthet Chem, New York, NY 10021 USA

[2] Cornell Univ, Joan & Sanford I Weill Grad Sch Med Sci, Sloan Kettering Div, New York, NY 10021 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2000年 / 122卷 / 28期

关键词：

D O I：

10.1021/ja001444y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：6803 / 6804

页数：2

共 22 条

[11] Production of the antitumor drug epirubicin (4′-epidoxorubicin) and its precursor by a genetically engineered strain of Streptomyces peucetius [J].

Madduri, K ;

Kennedy, J ;

Rivola, G ;

Inventi-Solari, A ;

Filippini, S ;

Zanuso, G ;

Colombo, AL ;

Gewain, KM ;

Occi, JL ;

MacNeil, DJ ;

Hutchinson, CR .

NATURE BIOTECHNOLOGY, 1998, 16 (01) :69-74

[12]

Omura S, 1984, MACROLIDE ANTIBIOTIC

[13] Bacterial polysaccharide synthesis and gene nomenclature [J].

Reeves, PR ;

Hobbs, M ;

Valvano, MA ;

Skurnik, M ;

Whitfield, C ;

Coplin, D ;

Kido, N ;

Klena, J ;

Maskell, D ;

Raetz, CRH ;

Rick, PD .

TRENDS IN MICROBIOLOGY, 1996, 4 (12) :495-503

[14]

REIST EJ, 1965, J ORG CHEM, P2312

[15] Enediyne biosynthesis and self-resistance: A progress report [J].

Thorson, JS ;

Shen, B ;

Whitwam, RE ;

Liu, W ;

Li, Y ;

Ahlert, J .

BIOORGANIC CHEMISTRY, 1999, 27 (02) :172-188

[16]

THORSON JS, 2000, IN PRESS CURR PHARM

[17] Genes and enzymes involved in deoxysugar biosynthesis in bacteria [J].

Trefzer, A ;

Salas, JA ;

Bechthold, A .

NATURAL PRODUCT REPORTS, 1999, 16 (03) :283-299

[18] The role of carbohydrates in biologically active natural products [J].

WeymouthWilson, AC .

NATURAL PRODUCT REPORTS, 1997, 14 (02) :99-110

[19] The gene calC encodes for a non-heme iron metalloprotein responsible for calicheamicin self-resistance in Micromonospora [J].

Whitwam, RE ;

Ahlert, J ;

Holman, TR ;

Ruppen, M ;

Thorson, JS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (07) :1556-1557

[20] Engineering a methymycin/pikromycin-calicheamicin hybrid: Construction of two new macrolides carrying a designed sugar moiety [J].

Zhao, LS ;

Ahlert, J ;

Xue, YQ ;

Thorson, JS ;

Sherman, DH ;

Liu, HW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (42) :9881-9882

← 1 2 3 →