Weight loss in Parkinson's disease

被引：240

作者：

Chen, HL

Zhang, SMM

Hernán, MA

Willett, WC

Ascherio, A

机构：

[1] Harvard Univ, Sch Publ Hlth, Dept Nutr, Boston, MA 02115 USA

[2] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA

[3] Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02115 USA

[4] Brigham & Womens Hosp, Dept Med, Channing Lab, Boston, MA USA

[5] Harvard Univ, Sch Med, Boston, MA USA

来源：

ANNALS OF NEUROLOGY | 2003年 / 53卷 / 05期

关键词：

D O I：

10.1002/ana.10577

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We prospectively examined the changes of body weight among 468 individuals with Parkinson's disease (PD) before and after the diagnosis. The average weight of PD patients was stable until shortly before the diagnosis (p for trend = 0.2) and then declined (p for trend < 0.0001). Interestingly, PD patients tended to increase their energy intakes as their weights decreased (p for trend < 0.002). In conclusion, weight loss in PD patients appears to be a continuous process that starts several years before the diagnosis and is not caused by reduced energy intake.

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页码：676 / 679

页数：4

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