Dihydromaltophilin;: A novel fungicidal tetramic acid containing metabolite from Streptomyces sp.

被引：64

作者：

Graupner, PR

Thornburgh, S

Mathieson, JT

Chapin, EL

Kemmitt, GM

Brown, JM

Snipes, CE ^{[1
]}

机构：

[1] DowElanco, Nat Prod Discovery, Indianapolis, IN 46268 USA

[2] DowElanco, Mol Spect, Indianapolis, IN 46268 USA

[3] DowElanco, Crop Dis Management, Indianapolis, IN 46268 USA

来源：

JOURNAL OF ANTIBIOTICS | 1997年 / 50卷 / 12期

关键词：

D O I：

10.7164/antibiotics.50.1014

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A new tetramic acid containing metabolite, A90931a has been isolated from Streptomyces sp., along with a second factor (A90931b) recently described and known as maltophilin. The structures were determined from spectroscopic data of the isolates and their acetylated products. A90931a was spectroscopically identical to the previously described antibiotic TAN-883b whose structure was not reported. A90931a and A90931b exhibit fungicidal activity against the grape pathogen Plasmopara viticola. Due to its similarity to maltophilin, A90931a has been called dihydromaltophilin.

引用

页码：1014 / 1019

页数：6

共 7 条

[1] DISCODERMIDE - A NEW BIOACTIVE MACROCYCLIC LACTAM FROM THE MARINE SPONGE DISCODERMIA-DISSOLUTA [J].