Effect of three-dimensional scaffold geometry on chondrocyte adhesion

被引：4

作者：

Lee, Seung-Jae ^{[1
]}

Kim, Byung ^{[1
]}

Lim, Geunbae ^{[1
]}

Kim, Sung-Won ^{[2
]}

Rhie, Jong-Won ^{[3
]}

Cho, Dong-Woo ^{[1
]}

机构：

[1] Pohang Univ Sci & Technol, Dept Mech Engn, Pohang 790784, South Korea

[2] Catholic Univ, Coll Med, Dept Otolaryngol HSN, Seoul 150712, South Korea

[3] Catholic Univ, Coll Med, Dept Plast Surg, Seoul 150712, South Korea

来源：

ASBM7: ADVANCED BIOMATERIALS VII | 2007年 / 342-343卷

关键词：

microstereolithography; scaffold; chondrocyte; geometry; adhesion;

D O I：

10.4028/www.scientific.net/KEM.342-343.97

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 [生物医学工程];

摘要：

This paper compares the characteristics of chondrocyte adhesion on two types of three-dimensional (3-D) scaffold: types A and B. These 3-D scaffolds can be repeatedly constructed with the same dimensions using microstereolithography, a system that allows the fabrication of pre-designed internal structures, such as pore size and porosity, by stacking the photopolymerized material. In tissue engineering, chondrocyte adhesion to a scaffold should have a major effect on the regeneration of cartilage. In this regard, we evaluated chondrocyte adhesion on two types of scaffold a lid found that chondrocyte adhesion was better on the type B scaffold than on the type A, demonstrating the importance of scaffold geometry in chondrocyte adhesion.

引用

页码：97 / +

页数：2