Anti-inflammatory activity of Indian black tea (Sikkim variety)

被引：37

作者：

Chaudhuri, AKN ^{[1
]}

Karmakar, S ^{[1
]}

Roy, D ^{[1
]}

Pal, S ^{[1
]}

Pal, M ^{[1
]}

Sen, T ^{[1
]}

机构：

[1] Jadavpur Univ, Dept Pharmaceut Technol, Div Pharmacol, Kolkata 700032, W Bengal, India

来源：

PHARMACOLOGICAL RESEARCH | 2005年 / 51卷 / 02期

关键词：

Camellia sinensis; Sikkim variety; anti-inflammatory; oedema; polyarthritis;

D O I：

10.1016/j.phrs.2004.07.008

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In this study, the anti-inflammatory (in reference to the cardinal signs of inflammation) and other related pharmacological activities of the hot water extract of black tea (Camellia sinensis, Sikkim variety) were evaluated along with certain standard drugs. The extract showed significant inhibitory activity against carrageenin, histamine, serotonin and prostaglandin-induced pedal inflammation. The extract inhibited exudative inflammation. The tea extract also inhibited cotton pellet-induced granuloma formation and adjuvant-induced polyarthritis. Black tea extract showed significant inhibition against glucose oxidase-mediated inflammation. The present observations establish the efficacy of this particular variety of black tea, both in the exudative and proliferative forms and as well in the chronic phase of inflammation. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：169 / 175

页数：7

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