Frequency analysis of autonomously oscillating yeast cultures

被引:11
作者
Birol, G [1 ]
Zamamiri, AQM [1 ]
Hjortso, MA [1 ]
机构
[1] Louisiana State Univ, Dept Chem Engn, Baton Rouge, LA 70803 USA
基金
美国国家科学基金会;
关键词
Saccharomyces cerevisiae; autonomous oscillations; Fourier transformation;
D O I
10.1016/S0032-9592(00)00144-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Measurements of state variables from oscillating chemostat cultures of Saccharomyces cerevisiae were analyzed by Fourier transformation. Of the signals tested, carbon dioxide and oxygen in the exit gas stream and dissolved oxygen in the medium, all gave identical results. Analysis of data from reactors operated at fixed conditions showed that after oscillations start, they pass through an extended transient lasting several days, before the oscillation period becomes constant. Under transient operating conditions, Fourier analysis revealed expected qualitative trends in the change of oscillation period with dilution rate. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:1085 / 1091
页数:7
相关论文
共 16 条
[1]   FLOW-CYTOMETRY AND CELL-CYCLE KINETICS IN CONTINUOUS AND FED-BATCH FERMENTATIONS OF BUDDING YEAST [J].
ALBERGHINA, L ;
RANZI, BM ;
PORRO, D ;
MARTEGANI, E .
BIOTECHNOLOGY PROGRESS, 1991, 7 (04) :299-304
[2]  
BEUCHAMP KG, 1974, SIGNAL PROCESSING US
[3]   OSCILLATORY BEHAVIOR OF SACCHAROMYCES-CEREVISIAE IN CONTINUOUS CULTURE .2. ANALYSIS OF CELL SYNCHRONIZATION AND METABOLISM [J].
CHEN, CI ;
MCDONALD, KA .
BIOTECHNOLOGY AND BIOENGINEERING, 1990, 36 (01) :28-38
[4]   OSCILLATORY BEHAVIOR OF SACCHAROMYCES-CEREVISIAE IN CONTINUOUS CULTURE .1. EFFECTS OF PH AND NITROGEN LEVELS [J].
CHEN, CI ;
MCDONALD, KA ;
BISSON, L .
BIOTECHNOLOGY AND BIOENGINEERING, 1990, 36 (01) :19-27
[5]   Population balance models of autonomous periodic dynamics in microbial cultures. Their use in process optimization [J].
Hjortso, MA .
CANADIAN JOURNAL OF CHEMICAL ENGINEERING, 1996, 74 (05) :612-620
[6]  
HJORTSO MA, 1995, J BIOTECHNOL, V42, P255
[7]   A CONCEPTUAL-MODEL OF AUTONOMOUS OSCILLATIONS IN MICROBIAL CULTURES [J].
HJORTSO, MA ;
NIELSEN, J .
CHEMICAL ENGINEERING SCIENCE, 1994, 49 (08) :1083-1095
[8]   INVOLVEMENT OF A CELL-SIZE CONTROL MECHANISM IN THE INDUCTION AND MAINTENANCE OF OSCILLATIONS IN CONTINUOUS CULTURES OF BUDDING YEAST [J].
MARTEGANI, E ;
PORRO, D ;
RANZI, BM ;
ALBERGHINA, L .
BIOTECHNOLOGY AND BIOENGINEERING, 1990, 36 (05) :453-459
[9]   THE DECISIVE ROLE OF THE SACCHAROMYCES-CEREVISIAE CELL-CYCLE BEHAVIOR FOR DYNAMIC GROWTH-CHARACTERIZATION [J].
MUNCH, T ;
SONNLEITNER, B ;
FIECHTER, A .
JOURNAL OF BIOTECHNOLOGY, 1992, 22 (03) :329-352
[10]   NEW INSIGHTS INTO THE SYNCHRONIZATION MECHANISM WITH FORCED SYNCHRONOUS CULTURES OF SACCHAROMYCES-CEREVISIAE [J].
MUNCH, T ;
SONNLEITNER, B ;
FIECHTER, A .
JOURNAL OF BIOTECHNOLOGY, 1992, 24 (03) :299-314