A 4D representation of DNA sequences and its application

被引:68
作者
Liao, B
Tan, MS
Ding, KQ
机构
[1] Chinese Acad Sci, Grad Sch, Dept Appl Math, Beijing 100049, Peoples R China
[2] Chongqing Three Gorges Univ, Chongqing 404000, Wanzhou, Peoples R China
基金
中国国家自然科学基金;
关键词
D O I
10.1016/j.cplett.2004.12.062
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 [物理化学]; 081704 [应用化学];
摘要
A 4D representation of DNA sequences has been derived for mathematical denotation of DNA sequence. The 4D representation also avoids loss of information accompanying alternative 2D and 3D representation. The geometrical centers of the 4D graph of DNA sequences indicate the distribution of base frequencies. A interesting phenomenon is observed for Goat and Gallus beta-globin genomes with high G + C content. The examination of similarities/dissimilarities among the coding sequences of the first exon of P-globin gene of different species illustrates the utility of the approach. (C) 2004 Published by Elsevier B.V.
引用
收藏
页码:380 / 383
页数:4
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