Recreational use of Aminorex and pulmonary hypertension

被引：26

作者：

Gaine, SP

Rubin, LJ ^{[1
]}

Kmetzo, JJ

Palevsky, HI

Traill, TA

机构：

[1] Univ Calif San Diego, Div Pulm & Crit Care Med, San Diego, CA 92103 USA

[2] Johns Hopkins Univ, Div Pulm & Crit Care Med, Baltimore, MD USA

[3] Johns Hopkins Univ, Div Cardiol, Baltimore, MD USA

[4] Doylestown Hosp, Div Cardiol, Doylestown, PA USA

[5] Univ Penn, Div Pulm & Crit Care Med, Philadelphia, PA 19104 USA

来源：

CHEST | 2000年 / 118卷 / 05期

关键词：

aminorex; illicit drug use; 4-methyl-aminorex; primary pulmonary hypertension;

D O I：

10.1378/chest.118.5.1496

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Pulmonary hypertension has been associated with ingestion of the appetite suppressant aminorex. A similar compound, 4-methyl-aminorex (street names, "U-4-E-uh" [pronounced euphoria] or "ice"), is a "designer" drug with central stimulant activity. This drug was discovered on the property of three individuals with diagnoses of pulmonary hypertension. The association between "recreational" aminorex manufacture and ingestion and the development of pulmonary hypertension is described.

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收藏

页码：1496 / 1500

页数：5

相关论文

共 17 条

[1] A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension [J].

Barst, RJ ;

Rubin, LJ ;

Long, WA ;

McGoon, MD ;

Rich, S ;

Badesch, DB ;

Groves, BM ;

Tapson, VF ;

Bourge, RC ;

Brundage, BH ;

Koerner, SK ;

Langleben, D ;

Keller, CA ;

Murali, S ;

Uretsky, BF ;

Clayton, LM ;

Jobsis, MM ;

Blackburn, SD ;

Shortino, D ;

Crow, JW .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (05) :296-301

[2] Frequency and clinical implications of increased pulmonary artery pressures in liver transplant patients [J].

Castro, M ;

Krowka, MJ ;

Schroeder, DR ;

Beck, KC ;

Plevak, DJ ;

Rettke, SR ;

Cortese, DA ;

Wiesner, RH .

MAYO CLINIC PROCEEDINGS, 1996, 71 (06) :543-551

[3]

HADENGUE A, 1991, GASTROENTEROLOGY, V100, P550

[4]

Kaisers U, 1996, Liver Transpl Surg, V2, P455, DOI 10.1002/lt.500020608

[5] Improvement in pulmonary hemodynamics during intravenous epoprostenol (prostacyclin): A study of 15 patients with moderate to severe portopulmonary hypertension [J].

Krowka, MJ ;

Frantz, RP ;

McGoon, MD ;

Severson, C ;

Plevak, DJ ;

Wiesner, RH .

HEPATOLOGY, 1999, 30 (03) :641-648

[6] Pulmonary hypertension: Considerations in the liver transplant candidate [J].

Kuo, PC .

TRANSPLANT INTERNATIONAL, 1996, 9 (02) :141-150

[7] Portopulmonary hypertension and the liver transplant candidate [J].

Kuo, PC ;

Plotkin, JS ;

Gaine, S ;

Schroeder, RA ;

Rustgi, VK ;

Rubin, LJ ;

Johnson, LB .

TRANSPLANTATION, 1999, 67 (08) :1087-1093

[8] Continuous intravenous infusion of epoprostenol for the treatment of portopulmonary hypertension [J].

Kuo, PC ;

Johnson, LB ;

Plotkin, JS ;

Howell, CD ;

Bartlett, ST ;

Rubin, LJ .

TRANSPLANTATION, 1997, 63 (04) :604-606

[9] PROGRESSIVE PLEXOGENIC PULMONARY-HYPERTENSION FOLLOWING LIVER-TRANSPLANTATION [J].

MANDELL, MS ;

GROVES, BM ;

DUKE, J .

TRANSPLANTATION, 1995, 59 (10) :1488-1490

[10] Pulmonary hypertension in chronic liver disease [J].

Mandell, MS ;

Groves, BM .

CLINICS IN CHEST MEDICINE, 1996, 17 (01) :17-&