Patent ductus arteriosus in the preterm infant: new insights into pathogenesis and clinical management

被引：25

作者：

Antonucci, Roberto ^{[1
]}

Bassareo, Pierpaolo ^{[2
]}

Zaffanello, Marco ^{[3
]}

Pusceddu, Michele ^{[4
,5
]}

Fanos, Vassilios ^{[4
,5
]}

机构：

[1] Nostra Signora di Bonaria Hosp, Div Neonatol & Pediat, San Gavino Monreale, Italy

[2] Univ Cagliari, Dept Cardiovasc & Neurol Sci, Cagliari, Italy

[3] Univ Verona, Dept Life & Reprod Sci, Sect Pediat, I-37100 Verona, Italy

[4] Univ Cagliari, Puericultura Inst, Neonatal Intens Care Unit, Cagliari, Italy

[5] Univ Cagliari, Neonatal Sect, Cagliari, Italy

来源：

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2010年 / 23卷

关键词：

Patent ductus arteriosus; pathogenesis; ibuprofen; indomethacin; preterm infant; PROSTAGLANDIN E-2; OXYGEN; RESPONSIVENESS; IBUPROFEN; FETAL; INDOMETHACIN; MECHANISMS; EXPRESSION; RECEPTORS; THERAPY;

D O I：

10.3109/14767058.2010.509920

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Postnatal closure of the ductus arteriosus is crucial in the circulatory adaptation of the newborn to extrauterine life. In recent years, many studies have been performed to improve our understanding of both the physiology of the ductus arteriosus in the fetus and newborn, and the mechanisms underlying persistent ductal patency in the preterm infant. The pharmacological treatment of patent ductus arteriosus (PDA) remains a controversial issue. This article reviews the recent literature on the pathogenesis and clinical management of PDA in the preterm infant.</.

引用

页码：34 / 37

页数：4

共 33 条

[1]

ABRAMS SE, 1995, BRIT HEART J, V73, P177

[2] Changes in urinary PGE2 after ibuprofen treatment in preterm infants with patent ductus arteriosus [J].

Antonucci, R. ;

Cuzzolin, L. ;

Arceri, A. ;

Dessi, A. ;

Fanos, V. .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2009, 65 (03) :223-230

[3] Urinary prostaglandin E2 in the newborn and infant [J].

Antonucci, Roberto ;

Cuzzolin, Laura ;

Arceri, Augusta ;

Fanos, Vassilios .

PROSTAGLANDINS & OTHER LIPID MEDIATORS, 2007, 84 (1-2) :1-13

[4]

Atzori Luigi, 2010, Front Biosci (Elite Ed), V2, P725, DOI 10.2741/e132

[5] Metabolomics: a new tool for the neonatologist [J].

Atzori, Luigi ;

Antonucci, Roberto ;

Barberini, Luigi ;

Griffin, Julian L. ;

Fanos, Vassilios .

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 2009, 22 :50-53

[6]

BALCOM RJ, 1993, PEDIATRICS, V91, P540

[7] Treatment of persistent patent ductus arteriosus in preterm infants: time to accept the null hypothesis? [J].

Benitz, W. E. .

JOURNAL OF PERINATOLOGY, 2010, 30 (04) :241-252

[8] Developmental changes in prostaglandin E2 receptor subtypes in porcine ductus arteriosus -: Possible contribution in altered responsiveness to prostaglandin E2 [J].

Bhattacharya, M ;

Asselin, P ;

Hardy, P ;

Guerguerian, AM ;

Shichi, H ;

Hou, X ;

Varma, DR ;

Bouayad, A ;

Fouron, JC ;

Clyman, RI ;

Chemtob, S .

CIRCULATION, 1999, 100 (16) :1751-1756

[9] RANDOMIZED TRIAL OF ORAL INDOMETHACIN AND TERBUTALINE SULFATE FOR THE LONG-TERM SUPPRESSION OF PRETERM LABOR [J].

BIVINS, HA ;

NEWMAN, RB ;

FYFE, DA ;

CAMPBELL, BA ;

STRAMM, SL .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1993, 169 (04) :1065-1070

[10] Characterization of PGE2 receptors in fetal and newborn lamb ductus arteriosus [J].

Bouayad, A ;

Kajino, H ;

Waleh, N ;

Fouron, JC ;

Andelfinger, G ;

Varma, DR ;

Skoll, A ;

Vazquez, A ;

Gobeil, F ;

Clyman, RI ;

Chemtob, S .

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2001, 280 (05) :H2342-H2349

← 1 2 3 4 →