Distribution of glucokinase, glucose transporter GLUT2, sulfonylurea receptor-1, glucagon-like peptide-1 receptor and neuropeptide Y messenger RNAs in rat brain by quantitative real time RT-PCR

被引：46

作者：

Li, B

Xi, XC

Roane, DS

Ryan, DH

Martin, RJ

机构：

[1] Louisiana State Univ, Pennington Biomed Res Ctr, Baton Rouge, LA 70808 USA

[2] Univ Louisiana Monroe, Dept Basic Pharmaceut Sci, Monroe, LA 71209 USA

来源：

MOLECULAR BRAIN RESEARCH | 2003年 / 113卷 / 1-2期

关键词：

glucose sensing; hypothalamus; hindbrain; real time RT-PCR;

D O I：

10.1016/S0169-328X(03)00125-6

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Glucokinase (GK), glucose transporter GLUT2, sulfonylurea receptor-1 (SUR1), glucagon-like peptide-1 receptor (GLP-1R) and neuropeptide Y (NPY) have been proposed to be involved in central glucose sensing or regulation of food intake. In this study, we combined tissue micropunch and real time reverse transcription polymerase chain reaction (RT-PCR), and measured GK, GLUT2, SUR1, GLP-1R and NPY mRNA expression in discrete areas in the hypothalamus and the hindbrain. (C) 2003 Elsevier Science B.V. All rights reserved.

引用

收藏

页码：139 / 142

页数：4

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