Cyclisation of 3-alkenylpyrido[1,2-a]pyrimidines to furo[2,3-d]pyrido[1,2-a]pyrimidines

被引：8

作者：

Güllü, M ^{[1
]}

Uzun, S ^{[1
]}

Yulçun, S ^{[1
]}

机构：

[1] Ankara Univ, Fac Sci, Dept Chem, TR-06100 Ankara, Turkey

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 09期

关键词：

cyclisation; furopyridopyrimidines; pyridopyrimidines;

D O I：

10.1016/S0040-4039(03)00087-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Alkenylpyrido[1,2-a]pyrimidines react under mild conditions to give novel tricyclic furo[2,3-d]pyrido[1,2-a]pyrimidines in high yields. The cyclisation takes place in the presence of an acid catalyst. The product yield is affected by the type and the strength of the acid used. Exceptionally high yields were obtained when an organic acid like trifluoromethanesulfonic acid and trifluoroacetic acid were used. On the other hand, sulfuric acid gave the best results of the inorganic acids examined. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：1939 / 1941

页数：3

共 6 条

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