Double infection with a resistant and a multidrug-resistant strain of Mycobacterium tuberculosis

被引:38
作者
Niemann, S [1 ]
Richter, E [1 ]
Rüsch-Gerdes, S [1 ]
Schlaak, M [1 ]
Greinert, U [1 ]
机构
[1] Natl Reference Ctr Mycobacteria, Forschungszentrum, D-23845 Borstel, Germany
关键词
D O I
10.3201/eid0605.000518
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
An immunocompetent patient was dually infected with a resistant and a multidrug-resistant strain of Mycobacterium tuberculosis (TB). The multidrug-resistant strain, which belongs to the W-strain/Beijing family, was first isolated after 3 months of therapy. Inappropriate treatment led to further drug resistance and unsuccessful therapy. Thus, additional infections with resistant M. tuberculosis strains should be considered when tuberculosis therapy fails.
引用
收藏
页码:548 / 551
页数:4
相关论文
共 11 条
[1]   PATTERNS OF INITIAL AND ACQUIRED ANTITUBERCULOSIS DRUG-RESISTANCE IN KARONGA DISTRICT, MALAWI [J].
GLYNN, JR ;
JENKINS, PA ;
FINE, PEM ;
PONNIGHAUS, JM ;
STERNE, JAC ;
MKANDWIRE, PK ;
NYASULU, S ;
BLISS, L ;
WARNDORFF, DK .
LANCET, 1995, 345 (8954) :907-910
[2]   SUPERINFECTION WITH RIFAMPIN-ISONIAZID-STREPTOMYCIN-ETHAMBUTOL (RISE)-RESISTANT TUBERCULOSIS IN 3 PATIENTS WITH AIDS - CONFIRMATION BY POLYMERASE CHAIN-REACTION FINGERPRINTING [J].
HORN, DL ;
HEWLETT, D ;
HAAS, WH ;
BUTLER, WR ;
ALFALLA, C ;
TAN, E ;
LEVINE, A ;
NAYAK, A ;
OPAL, SM .
ANNALS OF INTERNAL MEDICINE, 1994, 121 (02) :115-116
[3]   Simultaneous detection and strain differentiation of Mycobacterium tuberculosis for diagnosis and epidemiology [J].
Kamerbeek, J ;
Schouls, L ;
Kolk, A ;
vanAgterveld, M ;
vanSoolingen, D ;
Kuijper, S ;
Bunschoten, A ;
Molhuizen, H ;
Shaw, R ;
Goyal, M ;
vanEmbden, J .
JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (04) :907-914
[4]  
Moss AR, 1997, INT J TUBERC LUNG D, V1, P115
[5]   IS6110 fingerprinting of drug-resistant Mycobacterium tuberculosis strains isolated in Germany during 1995 [J].
Niemann, S ;
RuschGerdes, S ;
Richter, E .
JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (12) :3015-3020
[6]  
Niemann S, 1999, J CLIN MICROBIOL, V37, P409
[7]   Global surveillance for antituberculosis-drug resistance, 1994-1997 [J].
Pablos-Méndez, A ;
Raviglione, MC ;
Laszlo, A ;
Binkin, N ;
Rieder, HL ;
Bustreo, F ;
Cohn, DL ;
Lambregts-van Weezenbeek, CSB ;
Kim, SJ ;
Chaulet, P ;
Nunn, P .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (23) :1641-1649
[8]   Exogenous reinfection with multidrug-resistant Mycobacterium tuberculosis in an immunocompetent patient [J].
Shafer, RW ;
Singh, SP ;
Larkin, C ;
Small, PM .
TUBERCLE AND LUNG DISEASE, 1995, 76 (06) :575-577
[9]   EXOGENOUS REINFECTION WITH MULTIDRUG-RESISTANT MYCOBACTERIUM-TUBERCULOSIS IN PATIENTS WITH ADVANCED HIV-INFECTION [J].
SMALL, PM ;
SHAFER, RW ;
HOPEWELL, PC ;
SINGH, SP ;
MURPHY, MJ ;
DESMOND, E ;
SIERRA, MF ;
SCHOOLNIK, GK .
NEW ENGLAND JOURNAL OF MEDICINE, 1993, 328 (16) :1137-1144
[10]   MIXED-STRAIN INFECTION WITH A DRUG-SENSITIVE AND MULTIDRUG-RESISTANT STRAIN OF MYCOBACTERIUM-TUBERCULOSIS [J].
THEISEN, A ;
REICHEL, G ;
RUSCHGERDES, S ;
HAAS, WH ;
ROCKSTROH, JK ;
SPENGLER, U ;
SAUERBRUCH, T .
LANCET, 1995, 345 (8963) :1512-1513