African origin of GB virus C hepatitis G virus

被引：29

作者：

Tanaka, Y

Mizokami, M ^{[1
]}

Orito, E

Ohba, K

Kato, T

Kondo, Y

Mboudjeka, I

Zekeng, L

Kaptue, L

Bikandou, B

M'Pele, P

Takehisa, J

Hayami, M

Suzuki, Y

Gojobori, T

机构：

[1] Nagoya City Univ, Sch Med, Dept Med 2, Mizuho Ku, Nagoya, Aichi 467, Japan

[2] CHU Yaounde, Lab Hematol & Immunol, Yaounde, Cameroon

[3] Lab Natl Sante Publ, Brazzaville, Rep Congo

[4] Kyoto Univ, Inst Virus Res, Kyoto 606, Japan

[5] Natl Inst Genet, Ctr Informat Biol, Mishima, Shizuoka 411, Japan

来源：

FEBS LETTERS | 1998年 / 423卷 / 02期

关键词：

GB virus C; hepatitis G virus; Africa; Pygmy; indel; NS5A; phylogenetic analysis;

D O I：

10.1016/S0014-5793(98)00083-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Ninety-four GB virus C/hepatitis G virus (GBV-C/HGV) RNA-positive serum samples were obtained from all over the world, We found that all 15 GBV-C/HGV isolates from the Pygmies and the Bantu in the Central African region had a 12-amino acid indel (i.e. insertion or deletion) in the non-structural protein (NS) 5A region, Phylogenetic analyses of the NS5A region, using GBV-A as an outgroup, showed that these 15 isolates had diverged from the common ancestor much earlier than the remaining isolates, indicating an African origin of GBVC/HGV. (C) 1998 Federation of European Biochemical Societies.

引用

页码：143 / 148

页数：6

共 26 条

[1] CAUSES OF MORE FREQUENT DELETIONS THAN INSERTIONS IN MUTATIONS AND PROTEIN EVOLUTION
DEJONG, WW
RYDEN, L
[J]. NATURE, 1981, 290 (5802) : 157 - 159
[2] Molecular cloning and characterization of a GB virus C isolate from a patient with non-A-E hepatitis
Erker, JC
Simons, JN
Muerhoff, AS
Leary, TP
Chalmers, ML
Desai, SM
Mushahwar, IK
[J]. JOURNAL OF GENERAL VIROLOGY, 1996, 77 : 2713 - 2720
[3] FELSENSTEIN J, 1985, EVOLUTION, V39, P783, DOI 10.1111/j.1558-5646.1985.tb00420.x
[4] ESTIMATION OF AVERAGE NUMBER OF NUCLEOTIDE SUBSTITUTIONS WHEN THE RATE OF SUBSTITUTION VARIES WITH NUCLEOTIDE
GOJOBORI, T
ISHII, K
NEI, M
[J]. JOURNAL OF MOLECULAR EVOLUTION, 1982, 18 (06) : 414 - 423
[5] INA Y, 1994, COMPUT APPL BIOSCI, V10, P11
[6] GB virus-C/hepatitis G virus infection in an area endemic for viral hepatitis, chronic liver disease, and liver cancer
Kao, JH
Chen, PJ
Lai, MY
Chen, W
Liu, DP
Wang, JT
Shen, MC
Chen, DS
[J]. GASTROENTEROLOGY, 1997, 112 (04) : 1265 - 1270
[7] High prevalence of GB virus C/hepatitis G virus infection among the Jewish population in Uzbekistan
Kato, T
Mizokami, M
Nakano, T
Kondo, Y
Ohba, K
Orito, E
Ueda, R
Mukaide, M
Gurtsevitch, V
Syrtsev, A
Ruzibakiev, R
Abdurakhnamov, M
Yamashita, M
Hayami, M
[J]. VIRUS RESEARCH, 1997, 48 (01) : 81 - 87
[8] KONDO Y, 1997, IN PRESS VIRUS RES
[9] Leary TP, 1996, J MED VIROL, V48, P60, DOI 10.1002/(SICI)1096-9071(199601)48:1&lt
[10] 60::AID-JMV10&gt

← 1 2 3 →