Dissecting the biology of a pathogen during infection

被引:47
作者
Heithoff, DM [1 ]
Conner, CP [1 ]
Mahan, MJ [1 ]
机构
[1] Univ Calif Santa Barbara, Dept Mol Cellular & Dev Biol, Santa Barbara, CA 93106 USA
关键词
D O I
10.1016/S0966-842X(97)01153-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In vivo expression studies reveal many bacterial genes that contribute to the fitness of the organism in the context of host ecology. This collection of virulence genes defines the unique lifestyle of a pathogen during infection, pointing to the functions that dictate host specificity, tissue tropism and disease manifestation.
引用
收藏
页码:509 / 513
页数:5
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