Aseptic loosening of a knee prosthesis as imaged on FDG positron emission tomography

被引：11

作者：

De Winter, F

Van de Wiele, C

De Clercq, D

Vogelaers, D

De Bondt, P

Dierckx, RA

机构：

[1] State Univ Ghent, Div Nucl Med, Ghent, Belgium

[2] State Univ Ghent, Div Internal Med, Sect Infect, Ghent, Belgium

[3] City Hosp, Dept Orthoped & Traumatol, Lokeren, Belgium

来源：

CLINICAL NUCLEAR MEDICINE | 2000年 / 25卷 / 11期

关键词：

fluorodeoxyglucose; infection; knee loosening; prosthesis; positron emission tomography;

D O I：

10.1097/00003072-200011000-00017

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

FDG positron emission tomography (PET) has been presented as a highly accurate technique (n = 51; accuracy 96%, no false-positive results) for diagnosing chronic osteomyelitis. The authors report a case of high FDG uptake in aseptic loosening of a knee prosthesis. The FDG uptake mechanism in infection is related to increased tracer accumulation in activated macrophages, leukocytes, and fibroblasts. Macrophages and fibroblasts also play a role in aseptic loosening. This may be reflected in an elevated FDG uptake. Although promising, FDG PET probably will not be able to distinguish infection from inflammation. Further investigation is needed to determine its value in loosened prostheses.

引用

页码：923 / 923

页数：1

共 5 条

[1]

Guhlmann A, 1998, J NUCL MED, V39, P2145

[2]

KUBOTA R, 1992, J NUCL MED, V33, P1972

[3] Markers of connective tissue activation in aseptic hip prosthetic loosening [J].