Starring TREK-1 -: The next generation of vascular K+ channels

被引:14
作者
Bryan, Robert M., Jr.
Joseph, Biny K.
Lloyd, Eric
Rusch, Nancy J.
机构
[1] Univ Arkansas Med Sci, Dept Pharmacol & Toxicol, Little Rock, AR 72205 USA
[2] Baylor Coll Med, Dept Anesthesiol, Houston, TX 77030 USA
关键词
TREK-1; potassium channel; two pore domain; vascular smooth muscle; cerebral circulation; DOMAIN POTASSIUM CHANNELS; INDUCED INHIBITION; ARTERIES; KINASE; LEAK;
D O I
10.1161/CIRCRESAHA.107.157412
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:119 / 121
页数:3
相关论文
共 24 条
[1]   Polyunsaturated fatty acids are cerebral vasodilators via the TREK-1 potassium channel [J].
Blondeau, Nicolas ;
Petrault, Olivier ;
Manta, Stella ;
Giordanengo, Valerie ;
Gounon, Pierre ;
Bordet, Regis ;
Lazdunski, Michel ;
Heurteaux, Catherine .
CIRCULATION RESEARCH, 2007, 101 (02) :176-184
[2]   KCNK2: reversible conversion of a hippocampal potassium leak into a voltage-dependent channel [J].
Bockenhauer, D ;
Zilberberg, N ;
Goldstein, SAN .
NATURE NEUROSCIENCE, 2001, 4 (05) :486-491
[3]   Evidence for two-pore domain potassium channels in rat cerebral arteries [J].
Bryan, Robert M., Jr. ;
You, Junping ;
Phillips, Sharon C. ;
Andresen, Jon J. ;
Lloyd, Eric E. ;
Rogers, Paul A. ;
Dryer, Stuart E. ;
Marrelli, Sean P. .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2006, 291 (02) :H770-H780
[4]   A phospholipid sensor controls mechanogating of the K+ channel TREK-1 [J].
Chemin, J ;
Patel, AJ ;
Duprat, F ;
Lauritzen, I ;
Lazdunski, M ;
Honoré, E .
EMBO JOURNAL, 2005, 24 (01) :44-53
[5]   Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel [J].
Fink, M ;
Duprat, F ;
Lesage, F ;
Reyes, R ;
Romey, G ;
Heurteaux, C ;
Lazdunski, M .
EMBO JOURNAL, 1996, 15 (24) :6854-6862
[6]   Functional evidence of a role for two-pore domain potassium channels in rat mesenteric and pulmonary arteries [J].
Gardener, MJ ;
Johnson, IT ;
Burnham, MP ;
Edwards, G ;
Heagerty, AM ;
Weston, AH .
BRITISH JOURNAL OF PHARMACOLOGY, 2004, 142 (01) :192-202
[7]   Altered acetylcholine, bradykinin and cutaneous pressure-induced vasodilation in mice lacking the TREK1 potassium channel: the endothelial link [J].
Garry, Ambroise ;
Fromy, Berengere ;
Blondeau, Nicolas ;
Henrion, Daniel ;
Brau, Frederic ;
Gounon, Pierre ;
Guy, Nicolas ;
Heurteaux, Catherine ;
Lazdunski, Michel ;
Saumet, Jean Louis .
EMBO REPORTS, 2007, 8 (04) :354-359
[8]   International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels [J].
Goldstein, SAN ;
Bayliss, DA ;
Kim, D ;
Lesage, F ;
Plant, LD ;
Rajan, S .
PHARMACOLOGICAL REVIEWS, 2005, 57 (04) :527-540
[9]   Two-pore domain K channel, TASK-1, in pulmonary artery smooth muscle cells [J].
Gurney, AM ;
Osipenko, ON ;
MacMillan, D ;
McFarlane, KM ;
Tate, RJ ;
Kempsill, FEJ .
CIRCULATION RESEARCH, 2003, 93 (10) :957-964
[10]   TREK-1, a K+ channel involved in neuroprotection and general anesthesia [J].
Heurteaux, C ;
Guy, N ;
Laigle, C ;
Blondeau, N ;
Duprat, F ;
Mazzuca, M ;
Lang-Lazdunski, L ;
Widmann, C ;
Zanzouri, M ;
Romey, G ;
Lazdunski, M .
EMBO JOURNAL, 2004, 23 (13) :2684-2695