Carotenoid-radical interactions

被引:184
作者
Krinsky, NI [1 ]
Yeum, KJ
机构
[1] Tufts Univ, Dept Biochem, Sch Med, Boston, MA 02111 USA
[2] Tufts Univ, Jean Mayer USDA Human Nutr Res Ctr Aging, Boston, MA 02111 USA
关键词
D O I
10.1016/S0006-291X(03)00816-7
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Carotenoids have been reported to react with virtually any radical species likely to be encountered in a biological system. The products of such reactions are frequently short-lived radical species that can decay to more stable products. In some cases, stable adducts can be observed, but in the majority of interactions with radicals, carotenoids break down to degradation products very similar to what is seen with oxidative degradation. It is only recently that the biological activity of these breakdown products has begun to be investigated. (C) 2003 Elsevier Science (USA). All rights reserved.
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页码:754 / 760
页数:7
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