The chick: A great model system becomes even greater

被引：266

作者：

Stern, CD ^{[1
]}

机构：

[1] UCL, Dept Anat & Dev Biol, London WC1E 6BT, England

来源：

DEVELOPMENTAL CELL | 2005年 / 8卷 / 01期

关键词：

D O I：

10.1016/j.devcel.2004.11.018

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The chick embryo has a long and distinguished history as a major model system in developmental biology and has also contributed major concepts to immunology, genetics, virology, cancer, and cell biology. Now, it has become even more powerful thanks to several new technologies: in vivo electroporation (allowing gain- and loss-of-function in vivo in a time- and space-controlled way), embryonic stem (ES) cells, novel methods for transgenesis, and the completion of the first draft of the sequence of its genome along with many new resources to access this information. In combination with classical techniques such as grafting and lineage tracing, the chicken is now one of the most versatile experimental systems available.

引用

页码：9 / 17

页数：9

共 64 条

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