Functional connectivity in the brain -: is it an elusive concept?

被引:254
作者
Fingelkurts, AA
Fingelkurts, AA
Kähkönen, S
机构
[1] BM Sci Brain & Mind Technol Res Ctr, FI-02601 Espoo, Finland
[2] Univ Helsinki, Cent Hosp, BioMag Lab, FIN-00290 Helsinki, Finland
[3] Univ Helsinki, Cognit Brain Res Unit, Dept Psychol, FIN-00290 Helsinki, Finland
关键词
local/remote functional connectivity; brain synchronization; structural/operational synchrony; binding; neural assemblies; brain operations; EEG/MEG; quasi-stationary segments; metastability; operational modules; mental states;
D O I
10.1016/j.neubiorev.2004.10.009
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Even though functional brain connectivity is an influential concept in modem cognitive neuroscience, it is a very controversial notion. This is why further theoretical and methodological clarification are needed to help define precisely what is meant by functional connectivity and to help frame-associated issues. In this review we present the neurophysiological concept of functional connectivity, which utilizes in a plausible manner the notion of neural assemblies, as well as local and large-scale levels of description. Here functional connectivity is the mechanism for the coordination of activity between different neural assemblies in order to achieve a complex cognitive task or perceptual process. Our theoretical and empirical findings offer new insights into possible implications of the concept of functional connectivity for cognitive neuroscience. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:827 / 836
页数:10
相关论文
共 96 条
[1]  
Abeles M., 1991, Corticonics: Neural circuits of the cerebral cortex, DOI DOI 10.1017/CBO9780511574566
[2]   Use of the fractal dimension for the analysis of electroencephalographic time series [J].
Accardo A. ;
Affinito M. ;
Carrozzi M. ;
Bouquet F. .
Biological Cybernetics, 1997, 77 (5) :339-350
[3]   COMPUTER TECHNIQUES IN CORRELATION AND SPECTRAL ANALYSES OF CEREBRAL SLOW WAVES DURING DISCRIMINATIVE BEHAVIOR [J].
ADEY, WR ;
WALTER, DO ;
HENDRIX, CE .
EXPERIMENTAL NEUROLOGY, 1961, 3 (06) :501-&
[4]  
[Anonymous], 1983, SYNERGETICS BRAIN
[5]   Partial directed coherence:: a new concept in neural structure determination [J].
Baccalá, LA ;
Sameshima, K .
BIOLOGICAL CYBERNETICS, 2001, 84 (06) :463-474
[6]   Gamma, alpha, delta, and theta oscillations govern cognitive processes [J].
Basar, E ;
Basar-Eroglu, C ;
Karakas, S ;
Schürmann, M .
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, 2001, 39 (2-3) :241-248
[7]   Fast cortical selection: a principle of neuronal self-organization for perception? [J].
Bauer, R ;
Dicke, P .
BIOLOGICAL CYBERNETICS, 1997, 77 (03) :207-215
[8]   FUNCTIONAL CONNECTIVITY IN THE MOTOR CORTEX OF RESTING HUMAN BRAIN USING ECHO-PLANAR MRI [J].
BISWAL, B ;
YETKIN, FZ ;
HAUGHTON, VM ;
HYDE, JS .
MAGNETIC RESONANCE IN MEDICINE, 1995, 34 (04) :537-541
[9]   FEATURE EXTRACTION FROM ELECTROENCEPHALOGRAM BY ADAPTIVE SEGMENTATION [J].
BODENSTEIN, G ;
PRAETORIUS, HM .
PROCEEDINGS OF THE IEEE, 1977, 65 (05) :642-652
[10]   Nonlinear phase desynchronization in human electroencephalographic data [J].
Breakspear, M .
HUMAN BRAIN MAPPING, 2002, 15 (03) :175-198