Fetal heart modelling based on a pressure-volume relationship

被引:10
作者
Menigault, E
Vieyres, P
Pourcelot, L
Lepoivre, B
Durand, A
Berson, M
机构
[1] Fac Med Tours, INSERM U316, F-37032 Tours, France
[2] IUT Bourges, Lab Vis Robot, F-18020 Bourges, France
[3] Fac Med Tours, GIP Ultrasons, F-37032 Tours, France
关键词
human fetal circulation; heart mathematical model; varying elastance;
D O I
10.1007/BF02510983
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Study of the cardiovascular system of the human fetus is based on noninvasive measurement methods such as Doppler echography systems. The circulation conditions in fetal vessels are usually evaluated by resistance indices, giving limited physiological information on distal territories such as the placenta or the brain. To enhance the understanding of human fetal haemodynamics, a numerical model of the fetal heart has been developed, using the hydraulic-electric analogy. The model is based on a mechanical hypothesis of parallel functioning of the right and left ventricles, considered to have analogue elastance properties. Their behaviour is equivalent to that of a single ventricle ejecting an equivalent blood volume of 7 ml in the aorta. The characterisation of the equivalent ventricle is based on the determination of a set of four parameters (E-max, V-0, k(v) and P-0) representing the maximum ventricle contractility, a reference volume, and volume and pressure constants, respectively. The model proposed is validated by studying the effects of preload and afterload variations on the fetal heart work, and by comparing the numerical results with literature and measured data. The model constitutes the first step towards a global model of the cardiovascular system of the human fetus.
引用
收藏
页码:715 / 721
页数:7
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