Biological effects induced by nanosilver particles:: in vivo study

被引：40

作者：

Chen, Dandan ^{[1
]}

Xi, Tingfei

Bai, Jing

机构：

[1] Natl Inst Control Pharmaceut & Biol Prod, Beijing, Peoples R China

[2] Tsing Hua Univ, Beijing 100084, Peoples R China

来源：

BIOMEDICAL MATERIALS | 2007年 / 2卷 / 03期

关键词：

D O I：

10.1088/1748-6041/2/3/S08

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Nanosilver particles and microsilver particles were implanted into a rat's back muscle. The pathology and the local biocompatibility were observed and compared at days 7, 14, 30, 90 and 180 after implantation. A good biological effect was observed on days 7 and 14, both in rats treated with nanosilver particles and in rats treated with microsilver particles. A bad biological effect was observed at day 30, and the nanosilver-treated rats had more serious inflammation than the microsilver-treated rats.

引用

页码：S126 / S128

页数：3