Development of a cream from a self-emulsifying base and moisturizing actives

被引：19

作者：

Soriano, MMJ ^{[1
]}

Contreras, MJF ^{[1
]}

Flores, ES ^{[1
]}

机构：

[1] Alcala Univ, Fac Pharm, Dept Pharm & Pharmaceut Technol, Madrid 28871, Spain

来源：

FARMACO | 2001年 / 56卷 / 5-7期

关键词：

dermopharmaceutical form; pharmacotechnical study; rheology (thixotropy); stability; effectiveness assays;

D O I：

10.1016/S0014-827X(01)01087-4

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

This research study is based on the design and development of a semisolid emulsion system whose novel self-emulsifying base and preferentially moisturizing actives were investigated to find out whether the system mentioned could be used as a dermatological treatment for highly sensitive skins, including atopic ones. Thus, one of the main objectives of the present study consisted of in vivo evaluation of its effectiveness by means of non-invasive assessment techniques currently employed in cosmetology. Due to the fact that the new formula is, in principle, designed for skins that could present any kind of alteration, the current study was focused on rheological parameters of viscosity, thixotropy, and extensibility to guarantee not only an accurate assessment of composition but also a comfortable and safe application on skin. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

页码：513 / 522

页数：10

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