Micro-FT-IR spectroscopic studies of breast tissues

被引：5

作者：

Anastassopoulou, J. ^{[1
]}

Arapantoni, P. ^{[2
]}

Boukaki, E. ^{[1
]}

Konstadoudakis, S. ^{[2
]}

Theophanides, T. ^{[1
]}

Valavani, C. ^{[2
]}

Conti, C. ^{[3
]}

Ferraris, P. ^{[3
]}

Giorgini, G. ^{[3
]}

Sabbatini, S. ^{[3
]}

Tosi, G. ^{[3
]}

机构：

[1] Natl Tech Univ Athens, Dept Chem Engn, Zografou Campus, Zografos 15780, Greece

[2] Metaxa Hosp, Piraeus, Greece

[3] Univ Politecn Marche, Dipartimento Sci & Mat Terra, I-60131 Ancona, Italy

来源：

BRILLIANT LIGHT IN LIFE AND MATERIAL SCIENCES | 2007年

关键词：

breast cancer; osteosercoma; Micro-FT-IR; infrared; spectroscopy;

D O I：

10.1007/978-1-4020-5724-3_25

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Micro-FT-IR spectroscopy was used to study breast cancer tissues and, in particular osteosarcoma tissue. By analysing the spectra, we have found characteristic bands in the infrared regions, where the main components of these signature bands are located. In the region between 1680-1660 cm(-1) are found the characteristic bands of Amide I and II of proteins. The bands, which correspond to the vibrations of the phosphate groups, are found in the region near 1140-900 cm(-1). These characteristic bands have been monitored as a function of the degree of cancer progression. The results have been obtained with chernometric methods, such as cluster analysis, principal component analysis and custom analysis in order to distinguish the neoplastic zones from the normal zones.

引用

页码：273 / +

页数：3

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