Using a one-parameter model to sequentially estimate the root of a regression function

被引:4
作者
Shen, LZ
O'Quigley, J
机构
[1] Synteract Inc, Biostat, Encinitas, CA 92024 USA
[2] Univ Calif San Diego, Dept Math, La Jolla, CA 92093 USA
关键词
consistency; sequential design; stochastic approximation;
D O I
10.1016/S0167-9473(99)00107-3
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
This paper considers sequential estimation of the root of a regression function. We explore the possibility of using a one-parameter model to fit data that is collected sequentially and then calculate the value of the design variable for the next observation. This design value itself can serve as an estimator of the root. We find that when the design variable has continuous values, our estimates are consistent. However, when the design variable has discrete values, there are situations in which the estimates can get 'stuck' at the wrong value and the method then fails to converge to the correct point. Nonetheless under certain conditions, we can establish the consistency of the estimates even if the design variable is discrete. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:357 / 369
页数:13
相关论文
共 6 条
[1]  
[Anonymous], ADAPTIVE STAT PROCED
[2]  
HUBER PJ, 1967, 5TH P BERK S MATH ST, V1, P221
[3]   ADAPTIVE DESIGN AND STOCHASTIC-APPROXIMATION [J].
LAI, TL ;
ROBBINS, H .
ANNALS OF STATISTICS, 1979, 7 (06) :1196-1221
[4]   CONTINUAL REASSESSMENT METHOD - A PRACTICAL DESIGN FOR PHASE-1 CLINICAL-TRIALS IN CANCER [J].
OQUIGLEY, J ;
PEPE, M ;
FISHER, L .
BIOMETRICS, 1990, 46 (01) :33-48
[5]   A STOCHASTIC APPROXIMATION METHOD [J].
ROBBINS, H ;
MONRO, S .
ANNALS OF MATHEMATICAL STATISTICS, 1951, 22 (03) :400-407
[6]  
SILVAPULLE MJ, 1981, J ROY STAT SOC B MET, V43, P310