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Evolution by gene duplication: an update

被引：1566
作者：
Zhang, JZ [1 ]
机构：
[1] Univ Michigan, Dept Ecol & Evolutionary Biol, Ann Arbor, MI 48109 USA
来源：
TRENDS IN ECOLOGY & EVOLUTION | 2003年 / 18卷 / 06期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/S0169-5347(03)00033-8
中图分类号：
Q14 [生态学（生物生态学）];
学科分类号：
071012 ; 0713 ;
摘要：
The importance of gene duplication in supplying raw genetic material to biological evolution has been recognized since the 1930s. Recent genomic sequence data provide substantial evidence for the abundance of duplicated genes in all organisms surveyed. But how do newly duplicated genes survive and acquire novel functions, and what role does gene duplication play in the evolution of genomes and organisms? Detailed molecular characterization of individual gene families, computational analysis of genomic sequences and population genetic modeling can all be used to help us uncover the mechanisms behind the evolution by gene duplication.
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收藏
页码：292 / 298
页数：7
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