Glyco-quantum dots:: a new luminescent system with multivalent carbohydrate display

被引:68
作者
de la Fuente, JDM [1 ]
Penadés, S [1 ]
机构
[1] CSIC, Inst Invest Quim, Grp Carbohidrato, Lab Glyconanotechnol, Seville 41092, Spain
关键词
D O I
10.1016/j.tetasy.2004.12.002
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Nanoclusters of cadmium sulfide covalently bound to biologically significant neoglycoconjugates (glyco-QDs) have been synthesized by means of a single step solution procedure. The neoglycoconjugates confer the QDs water solubility, stability, and biological activity. The nanometer-sized glyco-QDs have been characterized by TEM, EDAX, H-1 NMR, UV-vis, and fluorescence spectroscopy. The carbohydrate conjugate nanocrystals can be used as bioactive fluorescence probes for specifically labeling carbohydrate cell receptors. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码:387 / 391
页数:5
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