Mechanochemical modification and synthesis of drugs

被引:90
作者
Boldyrev, VV
机构
[1] RAS, SB, Inst Solid State Chem & Mechanochem, Novosibirsk 630128, Russia
[2] Novosibirsk State Univ, Res & Educ Ctr Mol Design & Ecol Safe Technol, Novosibirsk 630090, Russia
关键词
D O I
10.1023/B:JMSC.0000039193.69784.1d
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Various aspects of the application of mechanochemistry and mechanical activation in the study of pharmaceutical materials are presented including the use of mechanical activation for modification of the physical and chemical properties of drugs and solid state synthesis of the drugs by mechanochemical methods. It is necessary to take the mechanochemical factors into account during grinding and tabletting the drugs. (C) 2004 Kluwer Academic Publishers.
引用
收藏
页码:5117 / 5120
页数:4
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