3D bioprinting for cell culture and tissue fabrication

被引:62
作者
Jian, Honglei [1 ]
Wang, Meiyue [1 ]
Wang, Shengtao [1 ]
Wang, Anhe [1 ]
Bai, Shuo [1 ]
机构
[1] Chinese Acad Sci, State Key Lab Biochem Engn, Inst Proc Engn, Beijing 100190, Peoples R China
基金
中国国家自然科学基金;
关键词
3D bioprinting; Bioink; Cell culture; Tissue fabrication; Organoid; OF-THE-ART; INJECTABLE HYDROGELS; HYALURONIC-ACID; STEM-CELLS; HUMAN SKIN; BONE; CARTILAGE; SCAFFOLDS; DESIGN; VASCULARIZATION;
D O I
10.1007/s42242-018-0006-1
中图分类号
R318 [生物医学工程];
学科分类号
100103 [病原生物学];
摘要
Three-dimensional (3D) bioprinting is a computer-assisted technology which precisely controls spatial position of biomaterials, growth factors and living cells, offering unprecedented possibility to bridge the gap between structurally mimic tissue constructs and functional tissues or organoids. We briefly focus on diverse bioinks used in the recent progresses of biofabrication and 3D bioprinting of various tissue architectures including blood vessel, bone, cartilage, skin, heart, liver and nerve systems. This paper provides readers a guideline with the conjunction between bioinks and the targeted tissue or organ types in structuration and final functionalization of these tissue analogues. The challenges and perspectives in 3D bioprinting field are also illustrated.
引用
收藏
页码:45 / 61
页数:17
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