Engineering analysis of penile hemodynamic and structural-dynamic relationships: Part II - Clinical implications of penile buckling

被引:43
作者
Udelson, D
Nehra, A
Hatzichristou, DG
Azadzoi, K
Moreland, RB
Krane, RJ
de Tejada, IS
Goldstein, I
机构
[1] Boston Univ, Sch Med, Dept Urol, Boston, MA 02118 USA
[2] Boston Univ, Coll Engn, Dept Aerosp & Mech Engn, Boston, MA 02215 USA
关键词
penile rigidity; erectile physiology; impotence; biomedical engineering; penile buckling;
D O I
10.1038/sj.ijir.3900311
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose: Penile buckling force was analytically described in terms of its constituents. In addition, theoretically-derived buckling force data were compared to clinically measured data and the influence of each constituent on penile buckling force data was assessed. Methods: Using engineering buckling theory for a column, a mathematically-derived penile buckling model was developed which incorporated geometric and hemodynamic data obtained by dynamic infusion pharmacocavernosometry studies in 21 impotent patients (age 43, range 24-62 y) as well as penile tissue mechanical characteristics previously developed (Part I). Results: In 17 of 21 patients the mean difference between theoretically derived and clinically measured buckling force data was 0.33+/-0.25 kg (r=0.96). Factors which increased penile buckling forces were: (1) high intracavernosal pressure values (rigidity was related to pressure in an exponential-like fashion); (2) high penile aspect ratio (D/L) values (relatively large diameter/short length penile geometry) and high flaccid diameter; and (3) high cavernosal expandability values (a measure of the ability of the corpora to approach its erect volume with relatively low intracavernosal pressures). Conclusions: Pressure-volume data (pressure, geometry and tissue characteristics) obtained during erectile function testing have been shown, for the first time, to theoretically predict the magnitude of clinically-measured penile buckling forces.
引用
收藏
页码:25 / 35
页数:11
相关论文
共 15 条
  • [1] BEER FP, 1992, MECH MATER, P78
  • [2] BEER FP, 1992, MECH MATER, P635
  • [3] DESAI KM, 1988, BRIT J UROL, V61, P254
  • [4] TRABECULAR SMOOTH-MUSCLE MODULATES THE CAPACITOR FUNCTION OF THE PENIS - STUDIES ON A RABBIT MODEL
    DETEJADA, IS
    MOROUKIAN, P
    TESSIER, J
    KIM, JJ
    GOLDSTEIN, I
    FROHRIB, D
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY, 1991, 260 (05): : H1590 - H1595
  • [5] DROLLER MJ, 1993, JAMA-J AM MED ASSOC, V270, P83
  • [6] QUANTITATION OF CORPOREAL VENOUS OUTFLOW RESISTANCE IN MAN BY CORPOREAL PRESSURE-FLOW EVALUATION
    FREIDENBERG, DH
    BERGER, RE
    CHEW, DE
    IRETON, R
    ANSELL, JS
    SCHWARTZ, AN
    [J]. JOURNAL OF UROLOGY, 1987, 138 (03) : 533 - 538
  • [7] PREEXISTING VASCULAR PATHOLOGY IN DONOR AND RECIPIENT VESSELS DURING PENILE MICROVASCULAR ARTERIAL BYPASS-SURGERY
    HATZICHRISTOU, DG
    GOLDSTEIN, I
    QUIST, WC
    [J]. JOURNAL OF UROLOGY, 1994, 151 (05) : 1217 - 1224
  • [8] HIBBLER RC, 1983, ENG MECH STATICS DYN, P513
  • [9] KARACAN I, 1978, SLEEP DISORDERS DIAG, P353
  • [10] REFLEX CONTRACTIONS OF THE ISCHIOCAVERNOSUS MUSCLES FOLLOWING ELECTRICAL AND PRESSURE STIMULATIONS
    LAVOISIER, P
    PROULX, J
    COURTOIS, F
    [J]. JOURNAL OF UROLOGY, 1988, 139 (02) : 396 - 399