Pesticide exposure and risk of mild cognitive dysfunction

被引:59
作者
Bosma, H
van Boxtel, MPJ
Ponds, RWHM
Houx, PJ
Jolles, J
机构
[1] Maastricht Univ, Maastricht Brain & Behav Inst, Dept Psychiat & Neuropsychol, NL-6200 MD Maastricht, Netherlands
[2] Maastricht Univ, European Grad Sch Neurosci, NL-6200 MD Maastricht, Netherlands
关键词
D O I
10.1016/S0140-6736(00)02685-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Little Is known about the adverse effects of substances, such as pesticides and metals, on the development of mild cognitive dysfunction (MCD). Cross-sectional and prospective data from the Maastricht Aging Study were used to find out the potential neurotoxicity of particular substances. Exposure to pesticides, for example by arable farmers and gardeners, was associated with increased risks of MCD. Exposure to metals and organic solvents was not associated with MCD. Our findings might reflect subtle changes in brain function among people exposed to pesticides.
引用
收藏
页码:912 / 913
页数:2
相关论文
共 5 条
  • [1] HARTMAN D, 1988, NEUROPSYCHOLOGICAL T
  • [2] Long-term postoperative cognitive dysfunction in the elderly: ISPOCD1 study
    Moller, JT
    Cluitmans, P
    Rasmussen, LS
    Houx, P
    Rasmussen, H
    Canet, J
    Rabbitt, P
    Jolles, J
    Larsen, K
    Hanning, CD
    Langeron, O
    Johnson, T
    Lauven, PM
    Kristensen, PA
    Biedler, A
    van Beem, H
    Fraidakis, O
    Silverstein, JH
    Beneken, JEW
    Gravenstein, JS
    [J]. LANCET, 1998, 351 (9106) : 857 - 861
  • [3] Clinical evaluation of pesticide exposure and poisonings
    OMalley, M
    [J]. LANCET, 1997, 349 (9059) : 1161 - 1166
  • [4] Mild cognitive impairment: conceptual basis and current nosological status
    Ritchie, K
    Touchon, J
    [J]. LANCET, 2000, 355 (9199) : 225 - 228
  • [5] van Boxtel MPJ, 1998, J GERONTOL A-BIOL, V53, pM147