An improved synthesis of 6-O-monotosyl-6-deoxy-β-cyclodextrin

被引:117
作者
Zhong, N [1 ]
Byun, HS [1 ]
Bittman, R [1 ]
机构
[1] CUNY Queens Coll, Dept Chem & Biochem, Flushing, NY 11367 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S0040-4039(98)00417-1
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Addition of p-toluenesulfonic anhydride (Ts2O) to beta-cyclodextrin (CD) in water, followed by treatment with 10% aqueous NaOH solution for 10 min and removal of excess Ts2O by filtration, gave mono-6-deoxy-6-(O-p-toluenesulfonyl)-CD (1) in 61% yield. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:2919 / 2920
页数:2
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