Highly precise shape mimicry by a difluorotoluene deoxynucleoside, a replication-competent substitute for thymidine

被引：63

作者：

Guckian, KM ^{[1
]}

Kool, ET ^{[1
]}

机构：

[1] Univ Rochester, Dept Chem, Rochester, NY 14627 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1997年 / 36卷 / 24期

关键词：

carbohydrates; conformation; hydrogen bonds; nucleosides; structure elucidation;

D O I：

10.1002/anie.199728251

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：2825 / 2828

页数：4

共 22 条

[1] CRYSTALLOGRAPHIC EVIDENCE FOR INTRAMOLECULAR C-H...O INTERACTIONS IN PRINCIPAL NUCLEOSIDES - REFINEMENT OF THE CRYSTAL-STRUCTURE OF THYMIDINE
CHEKHLOV, AN
[J]. JOURNAL OF STRUCTURAL CHEMISTRY, 1995, 36 (01) : 155 - 161
[2] SYNTHESIS AND PROPERTIES OF OLIGONUCLEOTIDES CONTAINING 2'-DEOXYNEBULARINE AND 2'-DEOXYXANTHOSINE
ERITJA, R
HOROWITZ, DM
WALKER, PA
ZIEHLERMARTIN, JP
BOOSALIS, MS
GOODMAN, MF
ITAKURA, K
KAPLAN, BE
[J]. NUCLEIC ACIDS RESEARCH, 1986, 14 (20) : 8135 - 8153
[3] SPECIFIC MUTAGENIC EFFECT OF BASE ANALOGUES ON PHAGE-T4
FREESE, E
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1959, 1 (02) : 87 - 105
[4] BIOCHEMICAL BASIS OF DNA-REPLICATION FIDELITY
GOODMAN, MF
CREIGHTON, S
BLOOM, LB
PETRUSKA, J
[J]. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1993, 28 (02) : 83 - 126
[5] How good is fluorine as a hydrogen bond acceptor?
Howard, JAK
Hoy, VJ
OHagan, D
Smith, GT
[J]. TETRAHEDRON, 1996, 52 (38) : 12613 - 12622
[6] Kornberg A., 1992, DNA REPLICATION, P113
[7] LOEB LA, 1982, ANNU REV BIOCHEM, V52, P429
[8] A thymidine triphosphate shape analog lacking Watson-Crick pairing ability is replicated with high sequence selectivity
Moran, S
Ren, RXF
Kool, ET
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (20) : 10506 - 10511
[9] Difluorotoluene, a nonpolar isostere for thymine, codes specifically and efficiently for adenine in DNA replication
Moran, S
Ren, RXF
Rumney, S
Kool, ET
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (08) : 2056 - 2057
[10] CONFORMATIONAL-ANALYSIS OF THE DEOXYRIBOFURANOSE RING IN DNA BY MEANS OF SUMS OF PROTON-PROTON COUPLING-CONSTANTS - A GRAPHICAL-METHOD
RINKEL, LJ
ALTONA, C
[J]. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 1987, 4 (04) : 621 - 649

← 1 2 3 →