FK506 in the treatment of inflammatory skin disease: Promises and perspectives

被引：36

作者：

Michel, G ^{[1
]}

Kemeny, L ^{[1
]}

Homey, B ^{[1
]}

Ruzicka, T ^{[1
]}

机构：

[1] ALBERT SZENT GYORGYI MED UNIV,DEPT DERMATOL,H-6701 SZEGED,HUNGARY

来源：

IMMUNOLOGY TODAY | 1996年 / 17卷 / 03期

关键词：

D O I：

10.1016/0167-5699(96)80599-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The immunosuppressive macrolide drug Fk505 is currently gaining increasing importance in dermatopharmacology. Here, Gunter Michel and colleagues summarize the current state of research info tire molecular mechanisms responsible for the functional modulation of cell type other than T cells, particularly epidermal cells, by this drug.

引用

页码：106 / 108

页数：3

共 17 条

[1] ANTIINFLAMMATORY EFFECT OF FK-506 ON HUMAN SKIN MAST-CELLS [J].

DEPAULIS, A ;

STELLATO, C ;

CIRILLO, R ;

CICCARELLI, A ;

ORIENTE, A ;

MARONE, G .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1992, 99 (06) :723-728

[2] DIFFERENTIAL INHIBITION OF CUTANEOUS T-CELL-MEDIATED REACTIONS AND EPIDERMAL-CELL PROLIFERATION BY CYCLOSPORINE-A, FK-506, AND RAPAMYCIN [J].

DUNCAN, JI .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1994, 102 (01) :84-88

[3]

EBERLEINKONIG B, 1994, ALLERGO J, V3, P327

[4] IMMUNOPHILINS IN PROTEIN-FOLDING AND IMMUNOSUPPRESSION [J].

FRUMAN, DA ;

BURAKOFF, SJ ;

BIERER, BE .

FASEB JOURNAL, 1994, 8 (06) :391-400

[5] TACROLIMUS (FK-506) - A NEW THERAPEUTIC AGENT FOR SEVERE RECALCITRANT PSORIASIS [J].

JEGASOTHY, BV ;

ACKERMAN, CD ;

TODO, S ;

FUNG, JJ ;

ABUELMAGD, K ;

STARZL, TE .

ARCHIVES OF DERMATOLOGY, 1992, 128 (06) :781-785

[6] ROLE OF INTERLEUKIN-8 RECEPTOR IN SKIN [J].

KEMENY, L ;

RUZICKA, T ;

DOBOZY, A ;

MICHEL, G .

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 1994, 104 (04) :317-322

[7] THE INTERLEUKIN-8 RECEPTOR - A POTENTIAL TARGET FOR ANTIPSORIATIC THERAPY [J].

KEMENY, L ;

KENDERESSY, AS ;

OLASZ, E ;

MICHEL, G ;

RUZICKA, T ;

FARKAS, B ;

DOBOZY, A .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1994, 258 (03) :269-272

[8] TOPICAL FK506 - SUPPRESSION OF ALLERGIC AND IRRITANT CONTACT-DERMATITIS IN THE GUINEA-PIG [J].

LAUERMA, AI ;

STEIN, BD ;

HOMEY, B ;

LEE, CH ;

BLOOM, E ;

MAIBACH, HI .

ARCHIVES OF DERMATOLOGICAL RESEARCH, 1994, 286 (06) :337-340

[9]

LEMSTER BH, 1995, CLIN EXP IMMUNOL, V99, P148

[10] IMMUNOSUPPRESSIVE MACROLIDES OF THE TYPE FK-506 - A NOVEL CLASS OF TOPICAL AGENTS FOR TREATMENT OF SKIN DISEASES [J].

MEINGASSNER, JG ;

STUTZ, A .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1992, 98 (06) :851-855

← 1 2 →