Imatinib treatment: Specific issues related to safety, fertility, and pregnancy

被引:133
作者
Hensley, ML [1 ]
Ford, JM [1 ]
机构
[1] Novartis Pharmaceut, Dept Oncol Clin Res, Basel, Switzerland
关键词
D O I
10.1053/shem.2003.50038
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:21 / 25
页数:5
相关论文
共 11 条
[1]  
[Anonymous], 1998, REVISED COMMON TOXIC
[2]  
Buchdunger E, 1996, CANCER RES, V56, P100
[3]  
Buchdunger E, 2000, J PHARMACOL EXP THER, V295, P139
[4]   Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the philadelphia chromosome. [J].
Druker, BJ ;
Sawyers, CL ;
Kantarjian, H ;
Resta, DJ ;
Reese, SF ;
Ford, JM ;
Capdeville, R ;
Talpaz, M .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (14) :1038-1042
[5]   Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. [J].
Druker, BJ ;
Talpaz, M ;
Resta, DJ ;
Peng, B ;
Buchdunger, E ;
Ford, JM ;
Lydon, NB ;
Kantarjian, H ;
Capdeville, R ;
Ohno-Jones, S ;
Sawyers, CL .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 344 (14) :1031-1037
[6]   Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor [J].
Heinrich, MC ;
Griffith, DJ ;
Druker, BJ ;
Wait, CL ;
Ott, KA ;
Zigler, AJ .
BLOOD, 2000, 96 (03) :925-932
[7]   Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. [J].
Kantarjian, H ;
Sawyers, C ;
Hochhaus, A ;
Guilhot, F ;
Schiffer, C ;
Gambacorti-Passerini, C ;
Niederwieser, D ;
Resta, D ;
Capdeville, R ;
Zoellner, U ;
Talpaz, M ;
Druker, B .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (09) :645-652
[8]   Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia [J].
O'Brien, SG ;
Guilhot, F ;
Larson, RA ;
Gathmann, I ;
Baccarani, M ;
Cervantes, F ;
Cornelissen, JJ ;
Fischer, T ;
Hochhaus, A ;
Hughes, T ;
Lechner, K ;
Nielsen, JL ;
Rousselot, P ;
Reiffers, J ;
Saglio, G ;
Shepherd, J ;
Simonsson, B ;
Gratwohl, A ;
Goldman, JM ;
Kantarjian, H ;
Taylor, K ;
Verhoef, G ;
Bolton, AE ;
Capdeville, R ;
Druker, BJ ;
Durrant, S ;
Schwarer, A ;
Joske, D ;
Seymour, J ;
Grigg, A ;
Ma, D ;
Arthur, C ;
Bradstock, K ;
Joshua, D ;
Louwagie, A ;
Martiat, P ;
Straetmans, N ;
Bosly, A ;
Shustik, C ;
Lipton, J ;
Forrest, D ;
Walker, I ;
Roy, DC ;
Rubinger, M ;
Bence-Bruckler, I ;
Kovacs, M ;
Turner, AR ;
Birgens, H ;
Bjerrum, O ;
Facon, T .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (11) :994-1004
[9]   ARG tyrosine kinase activity is inhibited by ST1571 [J].
Okuda, K ;
Weisberg, E ;
Gilliland, DG ;
Griffin, JD .
BLOOD, 2001, 97 (08) :2440-2448
[10]   Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study [J].
Sawyers, CL ;
Hochhaus, A ;
Feldman, E ;
Goldman, JM ;
Miller, CB ;
Ottmann, OG ;
Schiffer, CA ;
Talpaz, M ;
Guilhot, F ;
Deininger, MWN ;
Fischer, T ;
O'Brien, SG ;
Stone, RM ;
Gambacorti-Passerini, CB ;
Russell, NH ;
Reiffers, JJ ;
Shea, TC ;
Chapuis, B ;
Coutre, S ;
Tura, S ;
Morra, E ;
Larson, RA ;
Saven, A ;
Peschel, C ;
Gratwohl, A ;
Mandelli, F ;
Ben-Am, M ;
Gathmann, I ;
Capdeville, R ;
Paquette, RL ;
Druker, BJ .
BLOOD, 2002, 99 (10) :3530-3539