A facile synthesis of phenylacetic acids via Willgerodt-Kindler reaction under PTC condition

被引：31

作者：

Alam, MM ^{[1
]}

Adapa, SR ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Inorgan Div, Hyderabad 500007, Andhra Pradesh, India

来源：

SYNTHETIC COMMUNICATIONS | 2003年 / 33卷 / 01期

关键词：

D O I：

10.1081/SCC-120015559

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

Phenylacetic acids are efficiently synthesized from acetophenones via thiomorpholides under Phase Transfer Catalytic (PTC) condition. The reaction proceeds efficiently by using triethyl benzyl ammonium chloride (TEBA) as PTC and the reaction time decreased dramatically upto 1/5th (24-5) to afford pure products in good to excellent yield.

引用

页码：59 / 63

页数：5

共 23 条

[1]

ALAN N, Patent No. 343900

[2]

ANDRE G, 2000, TETRAHEDRON LETT, V41, P7601

[3]

BABIN P, Patent No. 0061573

[4]

STRUCTURE-ACTIVITY STUDY ON THE INFLUENCE OF PHENOLIC-COMPOUNDS AND BIOFLAVONOIDS ON RAT RENAL PROSTAGLANDIN SYNTHETASE [J].

BAUMANN, J ;

BRUCHHAUSEN, FV ;

WURM, G .

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1979, 307 (01) :73-78

[5]

STUDIES ON PLANT GROWTH-REGULATING SUBSTANCES .33. INFLUENCE OF RING SUBSTITUENTS ON PLANT GROWTH-REGULATING ACTIVITY OF PHENYLACETIC ACCID [J].

CHAMBERLAIN, VK ;

WAIN, RL .

ANNALS OF APPLIED BIOLOGY, 1971, 69 (01) :65-+

[6]

CLAUSSNER A, Patent No. 0384842

[7]

DEHMLOW EV, 1993, ACS S SERIES, V659

[8]

FINKELSHTEIN JA, Patent No. 5312828

[9]

GRAY SL, Patent No. 0059882

[10]

JITENDRA KJ, 1974, J APPL CHEM BIOTECHN, V24, P105

← 1 2 3 →