G-quadruplex signaling probe for highly sensitive DNA detection

被引：10

作者：

Zhang, Songbai ^{[1
]}

Wu, Zai-Sheng ^{[1
]}

Qiu, Liping ^{[1
]}

Zhou, Hui ^{[1
]}

Shen, Guoli ^{[1
]}

Yu, Ruqin ^{[1
]}

机构：

[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 19期

基金：

中国国家自然科学基金;

关键词：

ELECTROCHEMICAL DETECTION; ELECTRON-TRANSFER; HYBRIDIZATION; REAGENTLESS; MICROARRAY; PLATFORM; TRANSDUCTION; FLUORESCENCE; MONOLAYERS; BIOSENSOR;

D O I：

10.1039/b926646a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ferrocene-conjugated oligonucleotides that can form intermolecular guanine (G)-quadruplexes are prepared and used as signaling probes for detecting target DNA, improving substantially assay characteristics (e.g. a considerably wider linear dynamic range and lower detection limit).

引用

收藏

页码：3381 / 3383

页数：3

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