Comparative in vitro activities of four new fluoroquinolones against Streptococcus pneumoniae determined by Etest

被引：3

作者：

Waites, K

Brookings, E

Nix, S

Robinson, A

Gray, B

Swiatlo, E

机构：

[1] Univ Alabama, Dept Pathol, Birmingham, AL 35233 USA

[2] Univ Alabama, Dept Med, Birmingham, AL 35233 USA

[3] Univ Alabama, Dept Hosp Labs, Birmingham, AL 35233 USA

[4] Univ Alabama, Dept Microbiol, Birmingham, AL 35233 USA

[5] Spartanburg Reg Healthcare Syst, Spartanburg, SC USA

来源：

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | 1998年 / 9卷 / 04期

关键词：

Streptococcus pneumoniae; fluoroquinolones; susceptibility testing; Etest;

D O I：

10.1016/S0924-8579(97)00053-8

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Clinafloxacin, levofloxacin, sparfloxacin and trovafloxacin were tested by Etest against 188 Streptococcus pneumoniae isolates. Clinafloxacin and trovafloxacin were 2-4-fold more potent than sparfloxacin and 8-fold more than levofloxacin. Two isolates, both serotype 6, with high-level quinolone resistance (greater than or equal to 8 mu g/ml) were detected. The Etest is a practical means for determining S. pneumoniae susceptibilities to new fluoroquinolones. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：215 / 218

页数：4

共 21 条

[1] In vitro activities of five fluoroquinolone compounds against strains of Streptococcus pneumoniae with resistance to other antimicrobial agents
Barry, AL
Fuchs, PC
Brown, SD
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (10) : 2431 - 2433
[2] In vitro activity of BAY 12-8039, a novel 8-methoxyquinolone, compared to activities of six fluoroquinolones against and Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis
Brueggemann, AB
Kugler, KC
Doern, GV
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (07) : 1594 - 1597
[3] Tentative interpretive criteria for testing the susceptibility of Streptococcus pneumoniae to eight fluoroquinolones
Fuchs, PC
Barry, AL
Brown, SD
[J]. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 1996, 26 (01) : 23 - 27
[4] Susceptibility of multi-resistant Streptococcus pneumoniae to ciprofloxacin, ofloxacin and levofloxacin
Fuchs, PC
Barry, AL
Brown, SD
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1997, 39 (05) : 671 - 672
[5] The bactericidal activity of levofloxacin compared with ofloxacin, D-ofloxacin, ciprofloxacin, sparfloxacin and cefotaxime against Streptococcus pneumoniae
George, J
Morrissey, I
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1997, 39 (06) : 719 - 723
[6] Comparison of Etest to broth microdilution method for testing Streptococcus pneumoniae susceptibility to levofloxacin and three macrolides
Gerardo, SH
Citron, DM
Claros, MC
Goldstein, EJC
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (10) : 2413 - 2415
[7] Activity of the new fluoroquinolone trovafloxacin (CP-99,219) against DNA gyrase and topoisomerase IV mutants of Streptococcus pneumoniae selected in vitro
Gootz, TD
Zaniewski, R
Haskell, S
Schmieder, B
Tankovic, J
Girard, D
Courvalin, P
Polzer, RJ
[J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1996, 40 (12) : 2691 - 2697
[8] Multicentre in-vitro evaluation of the susceptibility of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis to ciprofloxacin, clarithromycin, co-amoxiclav and sparfloxacin
HoogkampKorstanje, JAA
DirksGo, SIS
Kabel, P
Manson, WL
Stobberingh, EE
Vreede, RW
Davies, BI
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1997, 39 (03) : 411 - 414
[9] IN-VITRO ACTIVITY OF THE FLUOROQUINOLONE TROVAFLOXACIN AGAINST PENICILLIN-SUSCEPTIBLE AND PENICILLIN-RESISTANT STREPTOCOCCUS-PNEUMONIAE
KLUGMAN, K
WASAS, A
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1995, 36 (05) : 873 - 874
[10] In-vitro and in-vivo activity of trovafloxacin against Streptococcus pneumoniae
Klugman, KP
Gootz, TD
[J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1997, 39 : 51 - 55

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