The molecular and cellular aspects of arthritis due to alphavirus infections - Lesson learned from ross river virus

被引：56

作者：

Rulli, Nestor E. ^{[1
]}

Melton, Julian ^{[1
]}

Wilmes, Anja ^{[1
]}

Ewart, Gary ^{[1
]}

Mahalingam, Suresh ^{[1
]}

机构：

[1] Univ Canberra, Sch Hlth Sci, Ctr Virus Res, Canberra, ACT 2601, Australia

来源：

BIOLOGY OF EMERGING VIRUSES: SARS, AVIAN AND HUMAN INFLUENZA, METAPNEUMOVIRUS, NIPAH, WEST NILE, AND ROSS RIVER VIRUS | 2007年 / 1102卷

关键词：

alphavirus; Ross River virus; mouse model of disease; viral arthritis; macrophages;

D O I：

10.1196/annals.1408.007

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Alphaviruses such as the Sindbis-group viruses, Scandinavian Ockelbo virus, the African Asian chikungunya virus, the African O'nyong-nyong virus, the South American Mayaro virus, and the Australasian Barmah Forest and Ross River viruses, are commonly associated with outbreaks of acute and persistent arthritis and arthralgia in humans. The mechanisms by which these viruses cause arthritis/ arthralgia are poorly understood. This chapter summarizes our current understanding of viral arthritides using our newly developed mouse model of Ross River virus-induced joint and muscle inflammation.

引用

页码：96 / 108

页数：13

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