Transtaganolides A-D:: Movel metabolites from Thapsia transtagana

被引：40

作者：

Saouf, A

Guerra, FM

Rubal, JJ

Moreno-Dorado, FJ

Akssira, M

Mellouki, F

López, M

Pujadas, AJ

Jorge, ZD

Massanet, GM

机构：

[1] Univ Cadiz, Fac Ciencias, Dept Quim Organ, E-11510 Puerto Real, Cadiz, Spain

[2] Univ Hassan 2, Fac Sci & Tech, Mohammadia 20650, Morocco

[3] Univ La Laguna, Inst Biorgan Antonio Gonzalez, San Cristobal la Laguna 38205, Spain

[4] Univ Cordoba, Dept Ciencias & Recursos Agr & Forestales, E-14080 Cordoba, Spain

来源：

ORGANIC LETTERS | 2005年 / 7卷 / 05期

关键词：

D O I：

10.1021/ol047421w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Four novel and unusual C-19 compounds from Thapsia transtagana, named transtaganolides A-D, have been isolated. Their structures were established by physical methods, including X-ray analysis of transtaganolides A and B. This is the first time that a 7-methoxy-4,5-dihydro-3H-oxepin-2-one ring has been found in a natural product.

引用

页码：881 / 884

页数：4

共 12 条

[1] SIR97:: a new tool for crystal structure determination and refinement [J].

Altomare, A ;

Burla, MC ;

Camalli, M ;

Cascarano, GL ;

Giacovazzo, C ;

Guagliardi, A ;

Moliterni, AGG ;

Polidori, G ;

Spagna, R .

JOURNAL OF APPLIED CRYSTALLOGRAPHY, 1999, 32 :115-119

[2]

CHRISTENSEN SB, 1997, PROG CHEM ORG NAT PR, V71, P130

[3]

Gunes H. Semih, 2001, Journal of Faculty of Pharmacy of Gazi University, V18, P35

[4]

NONIUS R, 1998, NONIUS KAPPA CCD SER

[5] Processing of X-ray diffraction data collected in oscillation mode [J].

Otwinowski, Z ;

Minor, W .

MACROMOLECULAR CRYSTALLOGRAPHY, PT A, 1997, 276 :307-326

[6]

Pujades- Salva A. J., 2003, FLORA IBERICA, V10, P401

[7] PHYTOCHEMISTRY OF THE GENUS THAPSIA [J].

RASMUSSEN, U ;

CHRISTENSEN, SB ;

SANDBERG, F .

PLANTA MEDICA, 1981, 43 (04) :336-341

[8]

RASSMUSSEN U, 1978, ACTA PHARM SUEC, V15, P133

[9]

SHELDRICK GM, 1993, SHELXL 93 PROGRAM RE

[10]

Spek A. L., 2003, PLATON

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