3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase of Legionella pneumophila transfers two Kdo residues to a structurally different lipid a precursor of Escherichia coli

被引：12

作者：

Brabetz, N ^{[1
]}

Schirmer, CE ^{[1
]}

Brade, H ^{[1
]}

机构：

[1] Res Ctr Borstel, Ctr Med & Biosci, Dept Med & Biochem Microbiol, D-23845 Borstel, Germany

来源：

JOURNAL OF BACTERIOLOGY | 2000年 / 182卷 / 16期

关键词：

D O I：

10.1128/JB.182.16.4654-4657.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) transferase gene of Legionella pneumophila was cloned and sequenced. Despite remarkable structural differences in lipid A, the gene complemented a corresponding Escherichia coli mutant and was shown to encode a bifunctional enzyme which transferred 2 Kdo residues to a lipid A acceptor of E. coli.

引用

页码：4654 / 4657

页数：4

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