Menverins A-D, new highly oxygenated guaiane lactones from Hainan gorgonian Menella verrucosa (Brundin)

被引：31

作者：

Zhang, W

Guo, YW

Mollo, E

Cimino, G

机构：

[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Inst Materia Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China

[2] CNR, Ist Chim Biomol, I-80078 Naples, Italy

来源：

HELVETICA CHIMICA ACTA | 2004年 / 87卷 / 11期

关键词：

D O I：

10.1002/hlca.200490263

中图分类号：

O6 [化学];

学科分类号：

0703 [化学];

摘要：

Four new highly oxygenated guaiane lactones, menverins A-D (1-4), were isolated from the gorgonian Menella verrucosa (BRUNDIN) from the South China Sea. Their structures and relative configurations were elucidated on the basis of spectroscopic data. All compounds contain a conjugated alpha-methyl-substituted alpha,beta-unsaturated gamma-lactone moiety, a C(8)=C(9) conjugated with the gamma-lactone moiety, and an exocyclic methylene group at C(4) (trivial numbering).

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页码：2919 / 2925

页数：7

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