MicroRNAs as tumor suppressors

被引：134

作者：

Hammond, Scott M. ^{[1
]}

机构：

[1] Univ N Carolina, Dept Cell & Dev Biol, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA

来源：

NATURE GENETICS | 2007年 / 39卷 / 05期

关键词：

D O I：

10.1038/ng0507-582

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Human cancers are characterized by widespread reduction in microRNA gene expression, but what role does this have in the pathobiology of the disease? A new study proves that reduction in microRNA expression does indeed promote tumorigenesis, changing the way we think about cancer.

引用

页码：582 / 583

页数：2

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