Molecular epidemiology of the sil streptococcal invasive locus in group A streptococci causing invasive infections in French children

被引:18
作者
Bidet, Philippe
Courroux, Celine
Salgueiro, Christophe
Carol, Agnes
Mariani-Kurkdjian, Patricia
Bonacorsi, Stephane
Bingen, Edouard
机构
[1] Hop Robert Debre, Microbiol Serv, Lab Assoc CNR Streptocoques, Infect Streptocoque Grp A Enfant,AP HP, F-75395 Paris 19, France
[2] Univ Paris 07, UFR Med, EA 3105, Lab Etud Genet Bacterienne Infect Enfant, F-75221 Paris, France
关键词
D O I
10.1128/JCM.00104-07
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We found 31 different emm-toxin genotypes among 74 group A streptococcal isolates causing invasive infections in French children. The predominant emm types were emm1 (25%), emm3 (8%), emm4 (8%), emm6 (7%), and emm89 (9%). Sixteen percent of isolates harbored the streptococcal invasive locus, half of them belonging to emm4.
引用
收藏
页码:2002 / 2004
页数:3
相关论文
共 21 条
[1]   Sequencing emm-specific PCR products for routine and accurate typing of group a streptococci [J].
Beall, B ;
Facklam, R ;
Thompson, T .
JOURNAL OF CLINICAL MICROBIOLOGY, 1996, 34 (04) :953-958
[2]   Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus [J].
Beres, SB ;
Richter, EW ;
Nagiec, MJ ;
Sumby, P ;
Porcella, SF ;
Deleo, FR ;
Musser, JM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (18) :7059-7064
[3]   Genome sequence of a serotype M3 strain of group A Streptococcus:: Phage-encoded toxins, the high-virulence phenotype, and clone emergence [J].
Beres, SB ;
Sylva, GL ;
Barbian, KD ;
Lei, BF ;
Hoff, JS ;
Mammarella, ND ;
Liu, MY ;
Smoot, JC ;
Porcella, SF ;
Parkins, LD ;
Campbell, DS ;
Smith, TM ;
McCormick, JK ;
Leung, DYM ;
Schlievert, PM ;
Musser, JM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (15) :10078-10083
[4]   CLONAL BASIS FOR RESURGENCE OF SERIOUS STREPTOCOCCUS-PYOGENES DISEASE IN THE 1980S [J].
CLEARY, PP ;
KAPLAN, EL ;
HANDLEY, JP ;
WLAZLO, A ;
KIM, MH ;
HAUSER, AR ;
SCHLIEVERT, PM .
LANCET, 1992, 339 (8792) :518-521
[5]   Pathogenesis of group A streptococcal infections [J].
Cunningham, MW .
CLINICAL MICROBIOLOGY REVIEWS, 2000, 13 (03) :470-+
[6]   Group A streptococci in the 1990s [J].
Efstratiou, A .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2000, 45 :3-12
[7]   Transcriptional regulation of the sil locus by the SilCR signalling peptide and its implications on group A streptococcus virulence [J].
Eran, Yoni ;
Getter, Yoav ;
Baruch, Moshe ;
Belotserkovsky, Ilia ;
Padalon, Gilly ;
Mishalian, Inbal ;
Podbielski, Andreas ;
Kreikemeyer, Bernd ;
Hanski, Emanuel .
MOLECULAR MICROBIOLOGY, 2007, 63 (04) :1209-1222
[8]   Complete genome sequence of an M1 strain of Streptococcus pyogenes [J].
Ferretti, JJ ;
McShan, WM ;
Ajdic, D ;
Savic, DJ ;
Savic, G ;
Lyon, K ;
Primeaux, C ;
Sezate, S ;
Suvorov, AN ;
Kenton, S ;
Lai, HS ;
Lin, SP ;
Qian, YD ;
Jia, HG ;
Najar, FZ ;
Ren, Q ;
Zhu, H ;
Song, L ;
White, J ;
Yuan, XL ;
Clifton, SW ;
Roe, BA ;
McLaughlin, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (08) :4658-4663
[9]   Effect of a bacterial pheromone peptide on host chemokine degradation in group A streptococcal necrotising soft-tissue infections [J].
Hidalgo-Grass, C ;
Dan-Goor, M ;
Maly, A ;
Eran, Y ;
Kwinn, LA ;
Nizet, V ;
Ravins, M ;
Jaffe, J ;
Peyser, A ;
Moses, AE ;
Hanski, E .
LANCET, 2004, 363 (9410) :696-703
[10]   A locus of group A streptococcus involved in invasive disease and DNA transfer [J].
Hidalgo-Grass, C ;
Ravins, M ;
Dan-Goor, M ;
Jaffe, J ;
Moses, AE ;
Hanski, E .
MOLECULAR MICROBIOLOGY, 2002, 46 (01) :87-99