The subsyndromal phenomenology of borderline personality disorder: A 10-year follow-up study

被引:254
作者
Zanarini, Mary C.
Frankenburg, Frances R.
Reich, D. Bradford
Silk, Kenneth R.
Hudson, James I.
McSweeney, Lauren B.
机构
[1] McLean Hosp, Lab Study Adult Dev, Belmont, MA 02178 USA
[2] McLean Hosp, Psychiat Epidemiol Res Program, Belmont, MA 02178 USA
[3] Harvard Univ, Sch Med, Dept Psychiat, Boston, MA 02115 USA
关键词
D O I
10.1176/appi.ajp.164.6.929
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: The purpose of this study was to characterize the course of 24 symptoms of borderline personality disorder in terms of time to remission. Method: The borderline psychopathology of 362 patients with personality disorders, all recruited during inpatient stays, was assessed using two semistructured interviews of proven reliability. Of these, 290 patients met DSM-III-R criteria as well as Revised Diagnostic interview for Borderlines criteria for borderline personality disorder, and 72 met DSM-III-R criteria for another axis 11 disorder. Over 85% of the patients were reinterviewed at five distinct 2-year follow-up waves by interviewers blind to all previously collected information. Results: Among borderline patients, 12 of the 24 symptoms studied showed patterns of sharp decline over time and were reported at 10-year follow-up by less than 15% of the patients who reported them at baseline. The other 12 symptoms showed patterns of substantial but less dramatic decline over the follow-up period. Symptoms reflecting core areas of impulsivity (e.g., self-mutilation and suicide efforts) and active attempts to manage interpersonal difficulties (e.g., problems with demandingness/entitlement and serious treatment regressions) seemed to resolve the most quickly. In contrast, affective symptoms reflecting areas of chronic dysphoria (e.g., anger and loneliness/emptiness) and interpersonal symptoms reflecting abandonment and dependency issues (e.g., intolerance of aloneness and counterdependency problems) seemed to be the most stable. Conclusions: The results suggest that borderline personality disorder may consist of both symptoms that are manifestations of acute illness and symptoms that represent more enduring aspects of the disorder.
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页码:929 / 935
页数:7
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