The immune thrombocytopenic purpura (ITP) bleeding score: assessment of bleeding in patients with ITP

被引:141
作者
Page, Lemke K.
Psaila, Bethan
Provan, Drew
Hamilton, J. Michael
Jenkins, Julian M.
Elish, Andrew S.
Lesser, Martin L.
Bussel, James B.
机构
[1] Cornell Univ, Weill Med Coll, Div Pediat Hematol Oncol, New York, NY 10021 USA
[2] GlaxoSmithKline, R&D, Discovery Med, UP4455, Collegeville, PA USA
[3] Feinstein Inst Med Res, Biostat Unit, LIJ Hlth Syst, Manhasset, NY USA
关键词
platelets; bleeding scale; platelet function; wet purpura; intracranial haemorrhage;
D O I
10.1111/j.1365-2141.2007.06635.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A method for objective quantification of bleeding symptoms in immune thrombocytopenic purpura (ITP) has not been established. The ITP Bleeding Scale (IBLS) is a novel bleeding assessment system comprising 11 site-specific grades. Implementation of the IBLS on 100 patient visits revealed that although platelet count and large platelet count correlated well with bleeding symptoms overall, this relationship disappeared in marked thrombocytopenia. The IBLS is a useful clinical tool for monitoring bleeding and may be used to aid the development of laboratory parameters that correlate with underlying bleeding propensity in thrombocytopenia.
引用
收藏
页码:245 / 248
页数:4
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