Synthetic study of aquayamycin. Part 3. First total synthesis

被引：66

作者：

Matsumoto, T

Yamaguchi, H

Tanabe, M

Yasui, Y

Suzuki, K ^{[1
]}

机构：

[1] Tokyo Inst Technol, Dept Chem, Tokyo 1528551, Japan

[2] Japan Sci & Technol Corp, CREST, Tokyo 1528551, Japan

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 43期

关键词：

D O I：

10.1016/S0040-4039(00)01480-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first total synthesis of aquayamycin (1) has been accomplished. The crucial steps include (I) the Hauser reaction between 3-(phenylsulfonyl)phthalide 3 and cyclohexenone 4 to make up the linear BCD tricycle, and (2) the intramolecular pinacol coupling of keto aldehyde 7 to the full tetracyclic framework. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：8393 / 8396

页数：4

共 23 条

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