Synthesis and comparative lectin-binding affinity of mannosyl-coated β-cyclodextrin-dendrimer constructs

被引：84

作者：

Baussanne, I

Benito, JM

Mellet, CO

Fernández, JMG

Law, H

Defaye, J

机构：

[1] CSIC, Inst Invest Quim, E-41092 Seville, Spain

[2] CNRS, UMR 5063, F-38243 Meylan, France

[3] Univ Grenoble 1, Dept Pharmacochim Mol Glucides, F-38243 Meylan, France

[4] Univ Sevilla, Fac Quim, Dept Quim Organ, E-41071 Seville, Spain

来源：

CHEMICAL COMMUNICATIONS | 2000年 / 16期

关键词：

D O I：

10.1039/b003765f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Targeted drug delivery systems have been built from beta-cyclodextrin by monoconjugation with mannosyl-coated dendritic branches following an iterative thiourea-forming convergent strategy; the multivalent adducts showed high Concanavalin A lectin binding ability and intact inclusion capabilities.

引用

页码：1489 / 1490

页数：2

共 14 条

[1] Synthesis and biological evaluation of α-D-mannopyranoside-containing dendrimers [J].