Synthesis and self-assembly properties of peptide - Polylactide block copolymers

被引：90

作者：

Caillol, S

Lecommandoux, S

Mingotaud, AF

Schappacher, M

Soum, A

Bryson, N

Meyrueix, R

机构：

[1] ENSCPB, CNRS, UMR 5629, Lab Chim Polymeres Organ, F-33600 Pessac, France

[2] Flamel Technol, F-69693 Venissieux, France

来源：

MACROMOLECULES | 2003年 / 36卷 / 04期

关键词：

D O I：

10.1021/ma021187c

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Poly(L-lactide-b-gamma-benzyl glutamate) copolymers with various block lengths were synthesized by sequential ring-opening polymerization of L-lactide and N-carboxyanhydride of gamma-benzyl glutamate. The copolymers were characterized by SEC and NMR spectrometry. DSC and SAXS data suggested that the copolymers were phase-separated in domains containing either crystalline PLLA or liquid-crystalline columnar hexagonal morphology of PBLG. When varying the temperature, reversible local order-order transition could be observed on these diblock copolymers.

引用

页码：1118 / 1124

页数：7

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